PRIMARY STRUCTURE OF CAMP-GATED CHANNEL FROM BOVINE OLFACTORY EPITHELIUM
PRIMARY STRUCTURE OF CAMP-GATED CHANNEL FROM BOVINE OLFACTORY EPITHELIUM
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DOI：
10.1016/0014-5793(90)81226-e
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发表时间：
1990-09-17
期刊：
影响因子：
3.5
通讯作者：
KAUPP, UB
中科院分区：
文献类型：
--
作者：
LUDWIG, J;MARGALIT, T;KAUPP, UB
通过克隆和测序牛嗅上皮环磷酸腺苷（cAMP）门控通道的cDNA，测定了其氨基酸序列。它与视杆细胞的cGMP门控通道具有高度的序列同源性，表明环核苷酸门控通道属于一个新的遗传相关蛋白家族。
The complete amino-acid sequence of the bovine olfactory epithelium adenosine 3',5'cyclic monophosphate (cAMP)-gated channel has been determined by cloning and sequencing its cDNA. It exhibits a high degree of sequence homology with the cGMP-gated channel of rod photoreceptors, suggesting that cyclic nucleotide-gated channels fall into a new family of genetically related proteins.