Cervical cancer as a priority for prevention in different world regions: An evaluation using years of life lost

Cervical cancer as a priority for prevention in different world regions: An evaluation using years of life lost
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DOI:
10.1002/ijc.11719
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发表时间:
2004-04-10
影响因子:
6.4
通讯作者:
Zhang, ZF
Zhang, ZF
中科院分区:
医学1区
文献类型:
--
作者:
Yang, BH;Bray, FI;Zhang, ZF

文献摘要

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通过估算世界不同地区年轻和中年女性(25-64岁)的生命损失年数(YLL),评估了宫颈癌在几种重要死亡原因(癌症和其他疾病)中的相对重要性。对生命年进行加权以反映其对个人和社会的重要性。在全球范围内,子宫颈癌约占总(加权)YLL 的 2%,低于该年龄组的其他原因死亡。然而,它是拉丁美洲和加勒比地区YLL的最重要原因。撒哈拉以南非洲和中南亚人口稠密地区的癌症对 YLL 的贡献也最大,这些地区因癌症死亡的实际风险较高,但被非癌症死亡(艾滋病、结核病和孕产妇疾病)所掩盖。整体情况对所使用的年龄加权函数不是很敏感。事实上,大多数生命损失是可以预防的,而且已经开发出简单的技术使之变得可行,这意味着从低收入环境的资源分配角度来看,宫颈癌的发病率更高。 (C) 2004 Wiley-Liss, Inc.
The relative importance of cancer of the cervix among several important causes of mortality (from cancer and other diseases) has been evaluated by estimating the years of life lost (YLL) by young and middle-aged women (25-64 years old) in different regions of the world. The life years were weighted to reflect their importance to the individual and to society. On a global basis, cancer of the cervix is responsible for about 2% of the total (weighted) YLL, fewer than for other causes of mortality in this age group. However, it is the most important cause of YLL in Latin America and the Caribbean. It also makes the largest contribution to YLL from cancer in the populous regions of SubSaharan Africa and South-Central Asia where the actual risk of loss of life from this cause is higher, although overshadowed by noncancer deaths (from AIDS, TB and maternal conditions). The overall picture is not very sensitive to the age weighting function used. The fact that most of the loss of life is preventable, and that simple technologies have been developed that make this practicable, means that cervical cancer has an even higher profile from the perspective of resource allocation in low income settings. (C) 2004 Wiley-Liss, Inc.