Disseminated intravascular coagulation as the presenting sign of gastric cancer during pregnancy
Disseminated intravascular coagulation as the presenting sign of gastric cancer during pregnancy
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弥散性血管内凝血是妊娠期胃癌的表现
DOI：
10.1111/j.1447-0756.2011.01561.x
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Konishi I.
中科院分区：
文献类型：
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作者：
Takai H;Kondoh E;Sato Y;Kakui K;Tatsumi K;Konishi I.
怀孕期间的胃癌是罕见的，结果通常很差。一名36岁女性在妊娠28周时并发弥散性血管内凝血（DIC），她被诊断为胃癌伴骨髓转移。剖腹产后进行甲氨蝶呤（100 mg/m2）和5-氟尿嘧啶（600 mg/m2）序贯化疗。 通过输血和化疗成功地控制了DIC。她在门诊接受化疗。本报告是第二例孕妇DIC作为进展期胃癌的初始表现。及时的诊断和化疗增加了相对有利的结果的机会，即使是在晚期胃癌由于骨髓受累而出现DIC的情况下。
Gastric cancer during pregnancy is rare and the outcome is generally poor. A 36‐year‐old woman in the 28th week of gestation was complicated with disseminated intravascular coagulation (DIC), and she was diagnosed with gastric cancer with bone marrow metastasis. Cesarean delivery followed by sequential methotrexate (100 mg/m2) and 5‐fluorouracil (600 mg/m2) chemotherapy was conducted. DIC was successfully managed with blood transfusion and chemotherapy. She has received chemotherapy in the outpatient clinic. This report is the second case of a pregnant woman with DIC as the initial manifestation of advanced gastric cancer. Prompt diagnosis and chemotherapy increases the chances of a relatively favorable outcome even in advanced gastric cancer presenting with DIC due to bone marrow involvement.