Association between health literacy and mortality: a systematic review and meta-analysis.
Association between health literacy and mortality: a systematic review and meta-analysis.
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DOI：
10.1186/s13690-021-00648-7
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发表时间：
2021-07-01
期刊：
影响因子：
--
通讯作者：
Zhang F
中科院分区：
文献类型：
--
作者：
Fan ZY;Yang Y;Zhang F
通过系统回顾和荟萃分析，确定健康素养(HL)与死亡率之间的关系。使用PubMed和Web of Science数据库，使用相关关键词和明确的纳入和排除标准，检索从数据库开始到2020年7月发表的文献。搜索仅限于英文文章。两位评价者独立选择研究并提取数据。用STATA15.0软件估计HL与死亡率的合并相关系数及其95%可信区间(CI)。使用亚组分析、敏感性分析和Meta回归分析来探索潜在的异质性来源。使用纽卡斯尔-渥太华量表对纳入荟萃分析的原始研究的质量进行评估。使用漏斗图和Egger‘s检验来确定是否存在显著的发表偏倚。总体而言，纳入了19篇文章，总共报道了41,149个主题。11篇是前瞻性队列研究，所有文章都被认为质量“好”。使用最多的筛查工具是成人功能性健康素养简明测验S和简明健康素养筛查量表。在39,423名受试者中(两篇文章没有报告低HL患者的数量)，大约9202名(23%)HL不足或边缘HL。HL与死亡率的相关系数为1.2 5(95%CI = 0.2 5~0.44)。HL越低，死亡风险越高。这一发现应该得到仔细的考虑，并得到进一步研究的证实。
To identify the relationship between health literacy (HL) and mortality based on a systematic review and meta-analysis. Literature published from database inception until July 2020 was searched using the PubMed and Web of Science databases, using relevant keywords and clear inclusion and exclusion criteria. The search was limited to English language articles. Two reviewers independently selected studies and extracted data. Pooled correlation coefficients and their 95% confidence intervals (CI) between HL and mortality were estimated using Stata 15.0 software. Potential sources of heterogeneity were explored using subgroup analysis, sensitivity analysis, and meta-regression. Quality of the original studies that were included in the meta-analysis was evaluated using the Newcastle–Ottawa Scale. A funnel plot and Egger’s test were used to determine whether significant publication bias was present. Overall, 19 articles were included, reporting on a total of 41,149 subjects. Eleven were prospective cohort studies, and all articles were considered “good” quality. The most used screening instruments were the short Test of Functional Health Literacy (S-TOFHLA) in Adults and the Brief Health Literacy Screen (BHLS). Among 39,423 subjects (two articles did not report the number of patients with low HL), approximately 9202 (23%) had inadequate or marginal HL. The correlation coefficient between HL and mortality was 1.25 (95%CI = 0.25–0.44). Lower HL was associated with an increased risk of death. This finding should be considered carefully and confirmed by further research.
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