The trans-stilbene oxide-active glutathione transferase in human mononuclear leucocytes is identical with the hepatic glutathione transferase mu.
The trans-stilbene oxide-active glutathione transferase in human mononuclear leucocytes is identical with the hepatic glutathione transferase mu.
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人单核白细胞中的反式二苯乙烯氧化物活性谷胱甘肽转移酶与肝谷胱甘肽转移酶 mu 相同。
DOI：
10.1042/bj2460783
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
B. Mannervik
中科院分区：
文献类型：
--
作者：
J. Seidegård;C. Guthenberg;R. Pero;B. Mannervik
从人单核白细胞中提纯了一种对反式二苯乙烯高活性的谷胱甘肽转移酶(GT-tSBO)。只有大约50%的受试者表达GT-tSBO。根据活性测定、免疫学研究以及只有表达谷胱甘肽转移酶Mu的个体对反式二苯乙烯具有高活性的事实，推测肝转移酶Mu与单核白细胞中的谷胱甘肽转移酶(GT-tSBO)是相同的。
A glutathione transferase from human mononuclear leucocytes with high activity towards trans-stilbene oxide (GT-tSBO) was purified. GT-tSBO is expressed in only about 50% of the individuals studied. As judged from activity measurements, immunological studies and the fact that only those individuals who express glutathione transferase mu have high activity towards trans-stilbene oxide, it is concluded that the hepatic transferase mu is identical with the glutathione transferase (GT-tSBO) in mononuclear leucocytes.