LEG BLOOD FLOW DURING EXERCISE IN MAN
LEG BLOOD FLOW DURING EXERCISE IN MAN
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DOI：
10.1042/cs0410459
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发表时间：
1971-01-01
期刊：
影响因子：
6
通讯作者：
WAHREN, J
中科院分区：
文献类型：
--
作者：
JORFELDT, L;WAHREN, J
1.一个指示剂稀释技术被用来确定人腿血流在休息和运动。该方法基于将吲哚菁绿色输注到股动脉中，并在腹股沟韧带水平从股静脉采血。基于在股静脉中两个不同采样水平下发现相等的染料浓度，提供了染料和血液混合的证据。休息时平衡所需的最短输注时间为3分钟，运动时为1分钟20秒。对8名健康运动员在安静状态和直立运动状态下的下肢血流量进行了测定，分别以400、800和1200 kpm/min的速度在自行车测功仪上进行运动，发现下肢血流量与运动强度和肺氧摄取量呈线性关系.腿部摄氧量测量为血流量和股动静脉氧差的乘积。腿部摄氧量与工作强度和肺摄氧量均呈线性回归关系。运动时下肢机械效率平均为34%.根据肺氧摄取量和股动静脉氧差，提出了一个近似计算下肢血流量的公式。
1. An indicator-dilution technique was used to determine human leg blood flow at rest and during exercise. The method is based on the infusion of Indocyanine Green into the femoral artery with blood sampling from the femoral vein at the level of the inguinal ligament. Evidence for mixing of dye and blood is presented, based on the finding of equal dye concentrations at two different sampling levels in the femoral vein. The minimum time of infusion required for equilibration at rest is 3 min and during exercise 1 min 20 s.2. Leg blood flow was measured in eight healthy athletic subjects at rest and during upright exercise on a bicycle ergometer at 400, 800 and 1200 kpm/min. Linear relationships were found between blood flow on the one hand and work intensity and pulmonary oxygen uptake on the other.3. Leg oxygen uptake was measured as the product of blood flow and femoral arterio-venous oxygen difference. Linear regressions were found for leg oxygen uptake in relation to both work intensity and pulmonary oxygen uptake. Leg mechanical efficiency during exercise averaged 34%.4. A formula for the approximate calculation of leg blood flow is suggested, based on the pulmonary oxygen uptake and the femoral arterio-venous oxygen difference.