Late infection of hydroxyapatite orbital implants.
Late infection of hydroxyapatite orbital implants.
复制标题
羟基磷灰石眼眶植入物的晚期感染。
DOI：
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复制
发表时间：
1999
期刊：
影响因子：
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通讯作者：
P. Mckelvie
中科院分区：
文献类型：
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作者：
B. Sloan;A. McNab;P. Mckelvie
背景
羟基磷灰石义眼台的暴露和轻微并发症是常见的。感染似乎是罕见的，纤维血管植入羟基磷灰石植入物可能会减少感染和挤压的可能性比其他类型的眼眶植入物。
方法
我们描述了三例羟基磷灰石植入物的慢性低度感染，发生在明显不复杂的手术后的晚期，结膜丢失或暴露的微小或不明显的区域。
结果
3例中有2例培养出金黄色葡萄球菌。所有三个植入物最终都需要移除。在血管化和脓肿化植入物之间可以看到一种特殊的组织学模式。
结论
羟基磷灰石植入物的慢性感染可以发生在没有大的结膜缺陷或其他明显的危险因素的晚期。虽然植入物通过结膜裂口暴露于病原体可能是一个因素，但在其中一个或多个病例中，感染可能发生在植入物的无血管部分，在结膜破裂之前。
BACKGROUND
Exposure and minor complications of hydroxyapatite orbital implants are common. Infection appears to be rare and fibrovascular ingrowth into hydroxyapatite implants may make infection and extrusion less likely than with other types of orbital implant.
METHODS
We describe three cases of chronic low-grade infection of hydroxyapatite implants, occurring late after apparently uncomplicated surgery, with tiny or inapparent areas of conjunctival loss or exposure.
RESULTS
Two of the three cases grew Staphylococcus oureus on culture. All three implants ultimately needed to be removed. A characteristic histological pattern was seen, with abrupt transition between vascularized and abscessed implant.
CONCLUSIONS
Chronic infection of hydroxyapatite implants can occur late, in the absence of large conjunctival defects, or other obvious risk factors. While exposure of the implant to pathogens through a breach in the conjunctiva may have been a factor, it appeared that the infection may have arisen in an avascular portion of the implant prior to the conjunctival breakdown in one or more of these cases.
羟基磷灰石植入物血管化中锝骨扫描的临床病理学相关性。
DOI：
10.1001/archopht.1997.01100160343013
发表时间：
1997
期刊：
Archives of ophthalmology (Chicago, Ill. : 1960)
影响因子：
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作者：
Pacheco,EM;Civelek,AC;Natarajan,TK;D'Anna,SA;Iliff,NT;Green,WR
通讯作者：
Green,WR