The effect of visual experience on the development of functional architecture in hMT
The effect of visual experience on the development of functional architecture in hMT
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DOI：
10.1093/cercor/bhm018
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发表时间：
2007-12-01
期刊：
影响因子：
3.7
通讯作者：
Pietrini, Pietro
中科院分区：
文献类型：
--
作者：
Ricciardi, Emiliano;Vanello, Nicola;Pietrini, Pietro
我们研究了视觉hMT+皮层是否在感觉流的超模态表征中起作用，而不是由视觉心理意象介导。我们使用功能性磁共振成像来测量视觉和触觉流的被动感知过程中有视力和先天性失明个体的神经活动。视觉运动反应皮层，包括hMT+，被确定在外侧枕叶和下颞叶皮质的视力正常的受试者的视流反应。触觉流知觉在有视力的受试者激活了这些皮层区域的更前部，但停用了更后部。相比之下，盲人受试者的触觉流感知激活了整个范围，包括更后的部分。这些结果表明，触觉流的hMT+和周围皮层的激活是不介导的视觉心理意象和hMT+的功能组织可以发展到辅助触觉流知觉在没有任何视觉经验。此外，视觉体验导致运动响应枕颞叶皮层分为参与视觉和触觉流的表示的前部子区域和仅处理视觉流的后部子区域。
We investigated whether the visual hMT+ cortex plays a role in supramodal representation of sensory flow, not mediated by visual mental imagery. We used functional magnetic resonance imaging to measure neural activity in sighted and congenitally blind individuals during passive perception of optic and tactile flows. Visual motion-responsive cortex, including hMT+, was identified in the lateral occipital and inferior temporal cortices of the sighted subjects by response to optic flow. Tactile flow perception in sighted subjects activated the more anterior part of these cortical regions but deactivated the more posterior part. By contrast, perception of tactile flow in blind subjects activated the full extent, including the more posterior part. These results demonstrate that activation of hMT+ and surrounding cortex by tactile flow is not mediated by visual mental imagery and that the functional organization of hMT+ can develop to subserve tactile flow perception in the absence of any visual experience. Moreover, visual experience leads to a segregation of the motion-responsive occipitotemporal cortex into an anterior subregion involved in the representation of both optic and tactile flows and a posterior subregion that processes optic flow only.