Patterns of photoprotection following CDKN2A/p16 genetic test reporting and counseling
Patterns of photoprotection following CDKN2A/p16 genetic test reporting and counseling
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DOI：
10.1016/j.jaad.2008.12.034
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发表时间：
2009-05-01
影响因子：
13.8
通讯作者：
Leachman, Sancy A.
中科院分区：
文献类型：
--
作者：
Aspinwall, Lisa G.;Leaf, Saniantha L.;Leachman, Sancy A.
背景：黑色素瘤基因检测和咨询光保护行为的影响尚不清楚。方法：对59个CDKN2A/p16基因突变阳性家系成员报告的使用防晒霜、防护服和躲避阳光的情况进行评估，作为突变状态和黑色素瘤病史的函数，在测试报告之前、之后立即和之后1个月。结果：所有参与者组实施所有光保护行为的意向都增加了(P
Background: The impact of melanoma genetic testing and counseling photoprotective behaviors is Unknown.Objective. To determine if genetic testing and counseling alter compliance with photoprotection recommendations.Methods: Reported use of sunscreen, protective clothing, and sun avoidance by 59 members of CDKN2A/p16-mutation positive pedigrees was assessed as a function of mutation status and melanoma history, before, immediately after, and 1 month following test reporting.Results: Intentions to practice all photoprotective behaviors increased in all participant groups (P