Screening and quantification of emerging contaminants in Periyar River, Kerala (India) by using high-resolution mass spectrometry (LC-Q-ToF-MS)
Screening and quantification of emerging contaminants in Periyar River, Kerala (India) by using high-resolution mass spectrometry (LC-Q-ToF-MS)
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DOI：
10.1007/s10661-018-6745-9
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发表时间：
2018-05
影响因子：
3
通讯作者：
N. K. Khalid;Dineep Devadasan;U. Aravind;C. Aravindakumar
中科院分区：
文献类型：
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作者：
N. K. Khalid;Dineep Devadasan;U. Aravind;C. Aravindakumar
新出现的污染物（EC）在不同的水生系统中的存在可能会导致对水生生物的有害影响，并随后对人类健康。在目前的工作中，液相色谱耦合到四极杆飞行时间质谱仪（LC-Q-ToF-MS）被用来确定和定量的一系列EC在Periyar河在阿卢瓦地区，喀拉拉邦，印度。在分析之前，使用固相萃取（SPE）对水样进行预浓缩。使用电喷雾电离（ESI）以正和负电离模式探测化合物。对线性、检测限（LOD）、定量限（LOQ）、准确度和精密度（日内和日间）进行了方法验证。使用标准校准曲线定量EC。已确定的9种EC包括药物、个人护理产品、类固醇、表面活性剂和邻苯二甲酸酯。在2-十二烷基苯磺酸（1012 ng/l）中观察到相对较高的浓度，在木质素中观察到较低的浓度（4.3 ng/l;由于低于LOQ，该值仅为近似值）。此外，我们已经确定了另外28种有机化合物，使用非目标分析技术，其中7种化合物属于表面活性剂的类别。作为Periyar河EC的第一份报告，该数据非常重要，因为该河是喀拉拉邦最大和重要的河流之一，在该省有几个饮用水净化装置。
The presence of emerging contaminants (ECs) in different aquatic systems may contribute to hazardous effects on aquatic organisms and subsequently on human health. In the present work, liquid chromatography coupled to a quadrupole time of flight mass spectrometer (LC-Q-ToF-MS) was used to identify and quantify a series of ECs in Periyar River in Aluva region, Kerala, India. The water samples were pre concentrated using solid-phase extraction (SPE) prior to analysis. The compounds were probed in both positive and negative ionization mode using electro spray ionization (ESI). Method validations were performed for linearity, limit of detection (LOD), limit of quantification (LOQ), accuracy, and precision (intraday and inter day). The ECs were quantified using standard calibration curve. The identified nine ECs include pharmaceuticals, personal care products, steroids, surfactants, and phthalate. A relatively high concentration was observed in the case of 2-dodecyl benzene sulfonic acid (1012 ng/l) and low concentration was observed for lignocaine (4.3 ng/l; since this is below LOQ, the value is only approximate). In addition, we have identified another 28 organic compounds using the technique of non-target analysis out of which seven compounds fall in the category of surfactants. Being the first report on ECs in Periyar River, the data is very important as this river is one of the biggest and important rivers of Kerala having several purification units for drinking water in the province.