Germ cell sex determination: a collaboration between soma and germline.
Germ cell sex determination: a collaboration between soma and germline.
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DOI:
10.1016/j.ceb.2010.09.006
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发表时间:
2010-12
影响因子:
7.5
通讯作者:
Van Doren M
中科院分区:
文献类型:
--
作者:
Murray SM;Yang SY;Van Doren M
Sex determination is regulated very differently in the soma vs. the germline, yet both processes are critical for the creation of the male and female gametes. In general, the soma plays an essential role in regulating sexual identity of the germline. However, in some species, such as Drosophila and mouse, the sex chromosome constitution of the germ cells makes an autonomous contribution to germline sexual development. Here we review how the soma and germline cooperate to determine germline sexual identity for some important model systems, the fly, the worm and the mouse, and discuss some of the implications of “dual control” (soma plus germline) as compared to species where germline sex is dictated only by the surrounding soma.
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