The mouse genome database (MGD): genetic and genomic information about the laboratory mouse

The mouse genome database (MGD): genetic and genomic information about the laboratory mouse
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DOI:
10.1093/nar/27.1.95
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发表时间:
1999-01-01
影响因子:
14.9
通讯作者:
Eppig, JT
Eppig, JT
中科院分区:
生物学2区
文献类型:
--
作者:
Blake, JA;Richardson, JE;Eppig, JT

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小鼠基因组数据库(MGD)专注于整合有关实验室小鼠的作图,同源性,多态性和分子数据。基因的详细描述,包括它们的染色体位置,基因功能,疾病关联,突变表型,分子多态性和链接到代表性序列,包括EST,整合在MGD中,从实验到基因到基因组的信息的关联需要仔细协调和实施标准化词汇,独特的命名结构,以及来自多个来源的详细信息。这些信息与其他公共数据库相链接,这些公共数据库侧重于其他信息,如表达模式、序列、书目详细信息和大型映射面板数据。科学家们通过生成染色体委员会报告,咨询基因家族命名修订,并提供小鼠品系特征和新突变表型的描述来参与MGD数据的管理,MGD可在http://www.informatics.jax.org上访问。
The Mouse Genome Database (MGD) focuses on the integration of mapping, homology, polymorphism and molecular data about the laboratory mouse. Detailed descriptions of genes including their chromosomal location, gene function, disease associations, mutant phenotypes, molecular polymorphisms and links to representative sequences including ESTs are integrated within MGD, The association of information from experiment to gene to genome requires careful coordination and implementation of standardized vocabularies, unique nomenclature constructions, and detailed information derived from multiple sources. This information is linked to other public databases that focus on additional information such as expression patterns, sequences, bibliographic details and large mapping panel data. Scientists participate in the curation of MGD data by generating the Chromosome Committee Reports, consulting on gene family nomenclature revisions, and providing descriptions of mouse strain characteristics and of new mutant phenotypes, MGD is accessible at http://www.informatics.jax.org.