The Alzheimer diseases.
The Alzheimer diseases.
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阿尔茨海默病。
DOI：
10.1016/s0959-4388(96)80098-5
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发表时间：
1996
影响因子：
5.7
通讯作者：
Roses,AD
中科院分区：
文献类型：
--
作者：
Roses,AD
我们对阿尔茨海默病病因的理解正在迅速推进，这是由于发现了常染色体显性形式的疾病的相关基因突变，以及广泛证实了载脂蛋白E（常见形式阿尔茨海默病的主要易感基因）所起的作用。新的假设正在产生，旧的假设正在被修改，以解释新信息的财富。
Our understanding of the etiologies of the Alzheimer diseases is advancing rapidly, led by the discovery of relevant genetic mutations for autosomal-dominant forms of the disease and widespread confirmation of the role played by apolipoprotein E, the major susceptibility gene for the common form of Alzheimer's disease. New hypotheses are being generated and old hypotheses are being modified to account for the wealth of new information.