Microscale pH regulation by splitting water
Microscale pH regulation by splitting water
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DOI：
10.1063/1.3657928
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发表时间：
2011-12-01
期刊：
影响因子：
3.2
通讯作者：
Chang, Hsueh-Chia
中科院分区：
文献类型：
--
作者：
Cheng, Li-Jing;Chang, Hsueh-Chia
我们提出了一种简单，灵活的方法，通过注入可控量的质子和氢氧离子通过场增强的水分子的解离在微室中的pH值调节。在DC电压偏压下，集成在微流体装置中的聚合物双极膜产生并分离H+和OH-离子，而不会产生气体或由电子转移反应产生污染物。稳定的局部芯片上pH和pH梯度得以维持，无需稀释分析物浓度的额外酸性/碱性溶液。该方法可以为微流体中的pH控制提供更好的策略。(C)2011年美国物理学会。[doi：10.1063/1.3657928]
We present a simple, flexible approach for pH regulation in micro-chambers by injecting controllable amounts of protons and hydroxide ions via field-enhanced dissociation of water molecules. Under a DC voltage bias, the polymeric bipolar membranes integrated in microfluidics devices generate and separate H+ and OH- ions without gas production or contaminant generation resulting from electron-transfer reactions. Robust local on-chip pH and pH gradients are sustained with no need of additional acidic/basic solutions that dilute analyte concentrations. The method could provide a better strategy for pH control in microfluidics. (C) 2011 American Institute of Physics. [doi:10.1063/1.3657928]