Sweat Gland Carcinoma: Case Report and Review of the Literature
Sweat Gland Carcinoma: Case Report and Review of the Literature
复制标题
汗腺癌：病例报告及文献综述
作者：
I. Ashley;Mary SMITH‐REED;Ann Chernys
背景我们报告一位57岁的西班牙裔男性患有恶性结节性汗腺瘤。病人有三个活检证实的良性结节状汗腺瘤在左脸颊超过2年的时间。几个月后，第四个复发性病变具有恶性组织学。目的对这些罕见的汗腺癌和治疗方法知之甚少。我们回顾了有关汗腺癌的文献，以阐明这些肿瘤的性质和最佳治疗方案。方法回顾性分析76例已发表的病例资料，并将其制成表格进行统计学分析。结果平均年龄57岁，男女分布均匀。肿瘤分布：下肢，32.9%;上肢，27.6%;躯干，11.9%;头部，26.3%;颈部，1.3%。转移部位：淋巴结30.2%，脏器22%。恶性汗腺肿瘤有局部和区域淋巴结复发的倾向。淋巴结清扫，放疗和化疗的作用进行了审查。结论应通过进行结构良好的试验来正式确定治疗决定。
background We report a 57–year–old Hispanic man with malignant nodular hidradenoma. The patient had three biopsy–proven benign nodular hidradenomas over the left cheek over a 2–year period. A fourth recurrent lesion several months later had malignant histology. objective Little is known about these rare sweat gland carcinomas and treatment modalities. We reviewed the literature on sweat gland carcinomas to elucidate the nature of these tumors and best treatment course. method Review of 76 published cases with compilation of data in tabular form with statistical analysis. results The mean age was 57 years with equal male–to–female distribution. Tumor distribution is: lower extremities, 32.9%; upper extremities, 27.6%; trunk, 11.9%: head, 26.3%; neck, 1.3%. Metastatic sites are: lymph nodes, 30.2%: viscera, 22%. Malignant sweat gland neoplasms have a propensity for local and regional lymph node recurrence. The roles of lymph node dissection, radiation, and chemotherapy are reviewed. conclusion Treatment decisions should be formalized by conducting a well–structured trial.