EVIDENCE OF SPINAL TUBERCULOSIS AT THE BEGINNING OF THE 4TH MILLENNIUM BC FROM ARENE CANDIDE CAVE (LIGURIA, ITALY)
EVIDENCE OF SPINAL TUBERCULOSIS AT THE BEGINNING OF THE 4TH MILLENNIUM BC FROM ARENE CANDIDE CAVE (LIGURIA, ITALY)
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DOI：
10.1002/ajpa.1330720102
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发表时间：
1987-01-01
影响因子：
2.8
通讯作者：
SCARSINI, C
中科院分区：
文献类型：
--
作者：
FORMICOLA, V;MILANESI, Q;SCARSINI, C
本文描述了在利古里亚（意大利）的Arene Alberde洞穴发现的新石器时代骨骼脊柱结核样病变，代表了欧洲最早的结核病病例之一。该墓葬被认为是新石器时代中期（方口陶器文化），其地层可追溯到公元前4000年的上半期。这具头骨的后颅部分保存完好，属于一名年龄约15岁的男性，体型非常轻盈。T11、T12椎体完全破坏和T10、L1椎体部分破坏导致的下胸椎和上腰椎椎体的吸收性病变、塌陷和成角后凸是其主要病理特征。病变的形态、受累部位和标本的年龄与结核性脊柱炎（Pott病）的诊断一致。骨骼的极度纤细，沿着其他关于生命最后几年遭受的压力（哈里斯线，釉质发育不全）的研究，以及有限的骨骼再生，表明在青春期开始时出现了晚期疾病过程。葬礼仪式表明，这位青少年的社会融合并没有受到严重疾病的阻碍。
This paper describes tuberculosislike lesions affecting the spine of Neolithic skeleton found in Arene Candide cave (Liguria, Italy) and representing one of the earliest cases of this disease in Europe. The burial is attributed to middle Neolithic (square-mouthed pottery culture) whose layers date, by 14C, to the first half of the fourth millennium BC. The skeleton, well preserved in the postcranial portion, belongs to a male aged about 15 years having a very light body build. Resorptive lesions localized to the lower thoracic and upper lumbar vertebral bodies, collapse and angular kyphosis, resulting from complete destruction of T11 and T12 and partial destruction of T10 and L1, are the main pathologic features. The morphology of the lesions, sites involved, and age of the specimen are consistent with a diagnosis of tuberculosus spondylitis (Pott''s disease). The extreme gracility of the skeleton, along with other studies of stress (Harris lines, enamel hypoplasia) suffered during the last years of life, and the limited bony regeneration point to a disease process in it''s late phase having arisen at the beginning of adolescence. The funerary ritual suggests that the social integration of this adolescent was not prevented by the severe infirmity.