Prognostic value of inflammation-based scores in patients receiving radical resection for colorectal cancer
Prognostic value of inflammation-based scores in patients receiving radical resection for colorectal cancer
复制标题
基于炎症的评分对接受结直肠癌根治性切除术的患者的预后价值
DOI：
10.1186/s12885-018-4842-3
复制
发表时间：
2018-11-12
期刊：
影响因子：
3.8
通讯作者：
Xia, Liangping
中科院分区：
文献类型：
--
作者：
Wang, Fang;He, Wenzhuo;Xia, Liangping
BackgroundThe modified Glasgow Prognostic Score (mGPS) and the neutrophil-to-lymphocyte ratio (NLR) are conventional inflammation-based scores for colorectal cancer (CRC). The systemic inflammation score (SIS) has been shown to be more informative than the mGPS in CRC. The albumin-NLR, composed of albumin and the NLR, can also be a candidate for a valuable inflammation score. However, about the utility of the mGPS, SIS, and albumin-NLR for CRC patients who have received radical resections remains unclear.MethodsThis study enrolled 877 CRC patients, who underwent radical surgical resection between January 1, 2007 and December 31, 2014. The prognostic values of the mGPS, SIS, and albumin-NLR were compared by the Kaplan-Meier survival analysis, multivariate Cox regression modelling, and the time-dependent receiver operating characteristic curve analysis (ROC).ResultsIn the Kaplan-Meier analysis, all three inflammation scores were significantly associated with overall survival (OS) in the group including all the patients (mGPS, p=0.016; SIS, p
