Neutrophilic Fixed Drug Eruption

Neutrophilic Fixed Drug Eruption
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DOI:
10.1097/dad.0000000000000157
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发表时间:
2015-07-01
影响因子:
1.1
通讯作者:
Reddy, Vijaya B.
Reddy, Vijaya B.
中科院分区:
医学4区
文献类型:
--
作者:
Waldman, Leah;Reddy, Swathi B.;Reddy, Vijaya B.

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固定性药疹(FDE)是一种药物引起的皮肤反应,每次暴露于违规药物时,都会在同一个相当局部的部位复发。FDE的典型组织病理学表现为界面皮炎伴淋巴细胞炎性细胞浸润。一个不寻常的情况下,FDE在一个27岁的孕妇谁提出了广泛的病变和主要是嗜中性细胞浸润的组织病理学检查报告。
Fixed drug eruption (FDE) is a cutaneous reaction to a medication that recurs in the same fairly localized site with each exposure to the offending drug. The classical histopathologic findings in FDE consist of an interface dermatitis with predominantly lymphocytic inflammatory cell infiltrate. An unusual case of FDE in a 27-year-old pregnant woman who presented with widespread lesions and a predominantly neutrophilic infiltrate on histopathologic examination is reported.