Autoantibody Profiling in a Cohort of Pediatric and Adult Patients With Autoimmune Hepatitis
Autoantibody Profiling in a Cohort of Pediatric and Adult Patients With Autoimmune Hepatitis
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DOI：
10.1002/jcla.21813
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发表时间：
2016-01
影响因子：
2.7
通讯作者：
D. Villalta;E. Girolami;M. Alessio;M. C. Sorrentino;M. Tampoia;I. Brusca;M. Daves;B. Porcelli;G. Barberio;M. Conte;L. Pantarotto;N. Bizzaro
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文献类型：
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作者：
D. Villalta;E. Girolami;M. Alessio;M. C. Sorrentino;M. Tampoia;I. Brusca;M. Daves;B. Porcelli;G. Barberio;M. Conte;L. Pantarotto;N. Bizzaro
自身免疫性肝炎（AIH）是一种罕见的疾病，其特征是存在1型AIH（AIH-1）和2型AIH（AIH-2）的自身抗体。本研究的目的是使用间接免疫荧光（IIF）和一种新的多重线印迹试验来评估儿科和成人AIH患者队列中的自身抗体谱。
Autoimmune hepatitis (AIH) is a rare condition characterized by the presence of autoantibodies distinctive of type 1 AIH (AIH‐1) and type 2 AIH (AIH‐2). The aim of this study was to evaluate the autoantibody profile in a cohort of pediatric and adult AIH patients, using both indirect immunofluorescence (IIF) and a new multiplexed line‐blot assay.