Potential benefits of allogeneic bone marrow mesenchymal stem cells for wound healing.
Potential benefits of allogeneic bone marrow mesenchymal stem cells for wound healing.
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DOI：
10.1517/14712598.2011.606212
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发表时间：
2011-11
影响因子：
4.6
通讯作者：
Badiavas EV
中科院分区：
文献类型：
--
作者：
Badiavas AR;Badiavas EV
越来越明显的是，选择的成体干细胞具有参与受损和/或患病组织的修复和再生的能力。间充质干细胞是研究最多的成体干细胞之一，用于治疗各种疾病，包括伤口愈合。间充质干细胞的功能可能有益于皮肤伤口愈合的应用进行了审查。鉴于其体外扩增和免疫调节作用的潜力，自体和同种异体间充质干细胞似乎非常适合作为伤口愈合疗法。来自年轻健康供体的同种异体间充质干细胞可能比年龄和全身性疾病可能是重要因素的自体来源具有特别的优势。
It is becoming increasingly evident that select adult stem cells have the capacity to participate in repair and regeneration of damaged and/or diseased tissues. Mesenchymal stem cells have been among the most studied adult stem cells for the treatment of a variety of conditions including wound healing. Mesenchymal stem cell features potentially beneficial to cutaneous wound healing applications are reviewed. Given their potential for in vitro expansion and immune modulatory effects, both autologous and allogeneic mesenchymal stem cells appear to be well suited as wound healing therapies. Allogeneic mesenchymal stem cells derived from young healthy donors could have particular advantage over autologous sources where age and systemic disease can be significant factors.
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影响因子：
2.9
作者：
Badiavas, Evangelos V.;Ford, Dwayne;Maizel, Abby
通讯作者：
Maizel, Abby
影响因子：
2.6
作者：
Bartholomew, A;Sturgeon, C;Hoffman, R
通讯作者：
Hoffman, R
影响因子：
3.3
作者：
de la Garza-Rodea, Anabel S.;van der Velde-van Dijke, Ietje;Knaan-Shanzer, Shoshan
通讯作者：
Knaan-Shanzer, Shoshan
影响因子：
4
作者：
Bertani, N;Malatesta, P;Perris, R
通讯作者：
Perris, R
影响因子：
4
作者：
Brunswig-Spickenheier, Baerbel;Boche, Janna;Lange, Claudia
通讯作者：
Lange, Claudia