Advanced cardiac life support in out-of-hospital cardiac arrest.
Advanced cardiac life support in out-of-hospital cardiac arrest.
复制标题
DOI：
10.1056/nejmoa040325
复制
发表时间：
2004-08-12
影响因子：
158.5
通讯作者：
Lyver, M
中科院分区：
文献类型：
--
作者：
Stiell, IG;Wells, GA;Lyver, M
背景资料：安大略院前高级生命支持（OPALS）研究测试了在快速除颤程序中添加高级生命支持程序对院外心脏骤停后存活率的增量效应。方法：这个多中心，在17个城市进行了对照临床试验，制定了支持计划，并招募了5638名在医院外心脏骤停的患者。在这些患者中，1391例在快速除颤阶段入组，4247例在随后的高级生命支持阶段入组。护理人员接受了标准的高级生命支持培训，包括气管插管和静脉给药。结果：从快速除颤阶段到高级生命支持阶段，住院率显著增加（10.9%对14.6%，P
Background: The Ontario Prehospital Advanced Life Support (OPALS) Study tested the incremental effect on the rate of survival after out-of-hospital cardiac arrest of adding a program of advanced life support to a program of rapid defibrillation.Methods: This multicenter, controlled clinical trial was conducted in 17 cities before and after advanced-life-support programs were instituted and enrolled 5638 patients who had had cardiac arrest outside the hospital. Of those patients, 1391 were enrolled during the rapid-defibrillation phase and 4247 during the subsequent advanced-life-support phase. Paramedics were trained in standard advanced life support, which includes endotracheal intubation and the administration of intravenous drugs.Results: From the rapid-defibrillation phase to the advanced-life-support phase, the rate of admission to a hospital increased significantly (10.9 percent vs. 14.6 percent, P