Physiology and pharmacology of copper.
Physiology and pharmacology of copper.
复制标题
铜的生理学和药理学。
DOI：
10.1016/0163-7258(80)90019-4
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发表时间：
1980
影响因子：
13.5
通讯作者：
R. Österberg
中科院分区：
文献类型：
--
作者：
R. Österberg
血吸虫病是热带和亚热带地区最重要的公共卫生问题之一，据估计，可能有大约2- 3亿例病例（Cheng，1974），甚至更多的人面临感染的风险。人类血吸虫是二代吸虫，三种常见的感染人类的血吸虫具有相似的生命周期。它们具有世代交替，在终末脊椎动物宿主中具有成年体的有性生殖，在蜗牛中间宿主中具有无性生殖阶段。曼氏血吸虫和曼氏血吸虫的钉螺中间宿主。Haematobium是水生软体动物，而S.控制血吸虫病的不同方法包括对人类终末宿主的群体治疗、环境卫生、控制与水的接触和控制软体动物中间宿主。每一种方法都有其优点和缺点，并根据其应用的条件而或多或少有效。用灭螺剂控制蜗牛是减少传播的一种迅速有效的手段，如果与其他控制方法结合使用，其效率可能会提高。自从报道硫酸铜能有效杀死肝吸虫的蜗牛中间宿主以来，铜化合物一直被用作杀螺剂，
Schistosomiasis is one of the most important public health problems of tropical and subtropical regions and it has been estimated that there may be some 2-300 million cases (Cheng, 1974) and even more people exposed to the risk of infection. The human schistosomes, or blood flukes, are digenetic trematodes and the three species of schistosomes commonly infecting man have similar life-cycles. They have an alternation of generations with the sexual generation of adult schistosomes in the definitive vertebrate host and an asexual stage in a snail intermediate host. The snail intermediate hosts of Schistosoma mansoni and S. haematobium are aquatic moluscs while those of S. japonicum are amphibious.The different methods of control of schistosomiasis include mass therapy of the human definitive host, environmental sanitation, control of contact with water and control of the molluscan intermediate host. Each has advantages and disadvantages and may be more or less effective according to the conditions where they are applied. Snail control by molluscicides is a rapid and effective means of reducing transmission and its efficiency is likely to be increased if combined with other methods of control. Copper compounds have been continuously used as molluscicides since it was reported that copper sulphate was effective in killing the snail intermediate host of the liver fluke,