Adverse perinatal outcomes are significantly higher in severe gestational hypertension than in mild preeclampsia

Adverse perinatal outcomes are significantly higher in severe gestational hypertension than in mild preeclampsia
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DOI:
10.1067/mob.2002.120080
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发表时间:
2002-01-01
影响因子:
9.8
通讯作者:
Thurnau, G
Thurnau, G
中科院分区:
医学1区
文献类型:
--
作者:
Buchbinder, A;Sibai, BM;Thurnau, G

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目的:目前的文献强调蛋白尿和高血压的存在会增加不良结局的风险。本研究的目的是比较发生高血压疾病或无蛋白尿的妇女胎儿不良结局的频率。研究设计:本研究设计是一个二次分析的数据,从妇女谁曾在以前的怀孕先兆子痫(n = 598)谁参加了一个多中心试验阿司匹林预防先兆子痫。这些妇女没有慢性高血压或肾脏疾病史,在研究入选时血压正常。评估的孕产妇和围产期结局变量为早产,
OBJECTIVE: The current literature emphasizes increased risk of adverse outcomes in the presence of proteinuria and hypertension. The objective of this study was to compare the frequency of adverse fetal outcomes in women who developed hypertensive disorders with or without proteinuria.STUDY DESIGN: The study design was a secondary analysis of data from women who had preeclampsia in a previous pregnancy (n = 598) who were enrolled in a multicenter trial of aspirin for the prevention of preeclampsia. The women had no history of chronic hypertension or renal disease and were normotensive at study inclusion. The maternal and perinatal outcome variables assessed were preterm delivery at