High-Resolution In vivo Three-Dimensional Mapping of Blood Flow and Blood Vessels Using Advanced Multipoint Laser Doppler Velocimeter
High-Resolution In vivo Three-Dimensional Mapping of Blood Flow and Blood Vessels Using Advanced Multipoint Laser Doppler Velocimeter
复制标题
使用先进的多点激光多普勒测速仪对血流和血管进行高分辨率体内三维测绘
DOI：
10.1143/jjap.48.017002
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发表时间：
2009
影响因子：
1.5
通讯作者：
T. Hachiga
中科院分区：
文献类型：
--
作者：
T. Andoh;H. Ishida;S. Akiguchi;H. Shirakawa;Y. Kuraishi;T. Hachiga
使用先进的多点激光多普勒测速仪（LDV）进行了在体三维（3D）血流和血管的映射。我们开发了一个多点LDV系统，用于透明流体中数据的同时测量。为了将线性测量技术应用于一系列单点，构建了多点LDV。我们使用波长为785 nm的半导体激光器开发了一种先进的多点LDV，并能够改善不透明流体（如血液）的测量。先进的多点LDV可以通过扫描实现血流的高分辨率体内3D映射，特别是在小动脉和小静脉中。使用小鼠进行实验，因为在视觉上验证该动物耳朵上的动脉和静脉图案相对容易。然后通过测量区域的空间扫描实现微循环的3D映射。体内3D映射结果大致与小鼠耳朵的前后图片相关。
An in vivo three-dimensional (3D) mapping of blood flow and blood vessels was carried out using an advanced multipoint laser Doppler velocimeter (LDV). We developed a multipoint LDV system for the simultaneous measurement of data in transparent fluids. The multipoint LDV was constructed in order to apply linear measurement techniques to a series of single points. We developed an advanced multipoint LDV using a semiconductor laser with a wavelength of 785 nm, and were able to improve the measurement of opaque fluids, such as blood. An advanced multipoint LDV can enable the high-resolution in vivo 3D mapping of blood flow, particularly in small arterioles and venules, by scanning. An experiment was carried out using a mouse owing to the relative ease in visually verifying arterial and veinous patterns on the ear of this animal. Then a 3D mapping of the microcirculation was achieved through a spatial scan of the measurement area. The in vivo 3D mapping results roughly correlate with the front and rear pictures of the mouse's ear.
影响因子：
5.7
作者：
Koizumi, Takayuki;Abe, Mayumi;Sato, Yasufumi
通讯作者：
Sato, Yasufumi