Visual fixation patterns during reciprocal social interaction distinguish a subgroup of 6-month-old infants at-risk for autism from comparison infants
Visual fixation patterns during reciprocal social interaction distinguish a subgroup of 6-month-old infants at-risk for autism from comparison infants
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DOI：
10.1007/s10803-006-0342-4
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发表时间：
2007-01-01
影响因子：
3.9
通讯作者：
Rogers, Sally J.
中科院分区：
文献类型：
--
作者：
Merin, Noah;Young, Gregory S.;Rogers, Sally J.
31名自闭症儿童的兄弟姐妹和24名对照婴儿在6个月大时与照顾者进行社交互动，使用改进的静止面孔范式，通过闭路电视视频系统进行测试。在“静止的脸”范式中，母亲与婴儿互动，然后静止不动，表现出一张中性的、没有表情的脸，然后恢复互动。记录了三次实验中婴儿注视模式的眼动追踪数据。使用分层聚类分析，我们确定了一个亚组婴儿，在“静止脸”发作期间，母亲的眼睛相对于嘴巴的凝视减少了。在这个亚组的11个婴儿中，有10个有一个患有自闭症的哥哥姐姐。
Thirty-one infant siblings of children with autism and 24 comparison infants were tested at 6 months of age during social interaction with a caregiver, using a modified Still Face paradigm conducted via a closed-circuit TV-video system. In the Still Face paradigm, the mother interacts with the infant, then freezes and displays a neutral, expressionless face, then resumes interaction. Eye tracking data on infant visual fixation patterns were recorded during the three episodes of the experiment. Using a hierarchical cluster analysis, we identified a subgroup of infants demonstrating diminished gaze to the mother's eyes relative to her mouth during the Still Face episode. Ten out of the 11 infants in this subgroup had an older sibling with autism.