3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium:: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria
3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium:: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria
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DOI：
10.1039/b802215a
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发表时间：
2008-01-01
影响因子：
3.3
通讯作者：
Pope, Simon J. A.
中科院分区：
文献类型：
--
作者：
Amoroso, Angelo J.;Arthur, Richard J.;Pope, Simon J. A.
3-氯甲基吡啶基联吡啶fac三羰基正离子是一种硫醇反应性发光剂，具有长的发光寿命和大的斯托克斯位移，共定位研究表明其在线粒体中积累。这代表了（MLCT）-M-3发光剂在成像中特异性靶向生物实体的首次应用。
The 3-chloromethylpyridyl bipyridine fac tricarbonyl rhenium cation is a thiol-reactive luminescent agent with a long luminescence lifetime and large Stokes shift that is demonstrated by colocalisation studies to accumulate in mitochondria. This represents the first application of a (MLCT)-M-3 luminescent agent for the specific targeting of a biological entity in imaging.