CHANGES IN THE PHYSICAL PROPERTIES OF THE UTERINE CERVIX OF THE RAT DURING PREGNANCY
CHANGES IN THE PHYSICAL PROPERTIES OF THE UTERINE CERVIX OF THE RAT DURING PREGNANCY
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DOI：
10.1113/jphysiol.1959.sp006304
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发表时间：
1959-01-01
影响因子：
5.5
通讯作者：
HARKNESS, RD
中科院分区：
文献类型：
--
作者：
HARKNESS, MLR;HARKNESS, RD
非妊娠大鼠的子宫颈是一个紧凑的结构，含有5-10 g/100 g湿重胶原蛋白和仅约20- 30体积%的平滑肌。11- 12天妊娠大鼠的子宫颈与双情期动物没有显著差异，但从此时开始变化逐渐进行，直至妊娠结束。在怀孕期间，子宫颈的湿重增加约2.5倍，总胶原蛋白含量略低于2倍。这种胶原蛋白浓度的下降不能用平滑肌比结缔组织相对更大的生长来解释，因为数据表明平滑肌的比例在怀孕期间下降。详细报告了整个妊娠过程中宫颈组织的可扩展性。
The cervix in the non-pregnant rat is a compact structure containing 5-10 g/100 g wet weight collagen and only about 20-30% by volume smooth muscle. The cervix of 11- to 12-day pregnant rats does not differ significantly from diestrous animals but from this time on changes become progressive until the end of pregnancy. During pregnancy, the wet weight of the cervix increases about 2.5 times and the total collagen content somewhat less than 2 times. This drop in collagen concentration can not be accounted for by relatively greater growth of smooth muscle than connective tissue as data indicate that the proportion of smooth muscle decreases in pregnancy. Extensibility of the cervical tissue throughout the course of pregnancy is reported in detail.