Torsional optokinetic nystagmus: normal response characteristics
Torsional optokinetic nystagmus: normal response characteristics
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DOI：
10.1136/bjo.2003.028738
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发表时间：
2004-06-01
影响因子：
4.1
通讯作者：
Gottlob, I
中科院分区：
文献类型：
--
作者：
Farooq, SJ;Proudlock, FA;Gottlob, I
背景/目的：很少有研究探讨扭转视动性眼震（tOKN）的正常反应特征。方法：用正弦光栅以30 ~ 1000 °/s的速度顺时针和逆时针旋转诱发扭转OKN，观察刺激速度和中枢/外周刺激对扭转OKN的影响。为了研究中枢刺激的效果，刺激大小从2.86度到50.8度变化。在50.8 °刺激上放置一个人工暗点，从2.86 °变化到43.2 °，以研究外周刺激。每个实验有八名受试者参与，并使用视频眼电描记术记录扭转眼球运动。结果：在8degrees/s刺激时，获得最大增益。MSPV增加到200度/秒的刺激速度，在两个方向上达到最大30度/秒。MSPV与刺激速度的对数呈线性相关。以40度/秒旋转的最小场尺寸诱发的增益为最大显示引起的增益的10%。当使用最周边刺激时，增益维持在50%的增益诱发时，充分显示used.Conclusions：一个广泛的刺激速度可以引起tOKN和周边场刺激有助于其反应显着。
Background/aims: Few studies have investigated normal response characteristics of torsional optokinetic nystagmus (tOKN). The authors have investigated the effect of stimulus velocity and central/peripheral stimulation on tOKN.Methods: Torsional OKN was elicited using a sinusoidal grating rotating at velocities of 3degrees/s to 1000degrees/s in clockwise and anticlockwise directions. To investigate the effect of central stimulation, stimulus size was varied from 2.86degrees to 50.8degrees. An artificial scotoma placed over a 50.8degrees stimulus was varied from 2.86degrees to 43.2degrees to investigate peripheral stimulation. Eight subjects participated in each experiment and torsional eye movements were recorded using video-oculography. The mean slow phase velocity (MSPV) and gain were calculated.Results: The maximum gain occurred in response to 8degrees/s stimulation. The MSPV increased up to a stimulus velocity of 200degrees/s achieving a maximum of 3degrees/s in both directions. MSPV was linearly correlated with the log of stimulus velocity. The smallest field size, rotating at 40degrees/s, evoked 10% of the gain elicited by the largest display. When the most peripheral stimulus was used, the gain was maintained at 50% of the gain evoked when the full display was used.Conclusions: A wide range of stimulus velocities can elicit tOKN and peripheral field stimulation contributes significantly to its response.