Prevalence of and risk factors for subclinical cardiovascular disease in selected US hispanic ethnic groups
Prevalence of and risk factors for subclinical cardiovascular disease in selected US hispanic ethnic groups
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DOI：
10.1093/aje/kwm402
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发表时间：
2008-04-15
影响因子：
5
通讯作者：
Criqui, Michael H.
中科院分区：
文献类型：
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作者：
Allison, Matthew A.;Budoff, Matthew J.;Criqui, Michael H.
在这项研究中，作者确定了四个美国西班牙裔亚组中心血管疾病（CVD）危险因素和亚临床CVD的患病率和程度，以及这些组中CVD危险因素和亚临床CVD之间的相关性。参与者是2000-2002年参加多种族动脉粥样硬化研究的1,437名西班牙裔男性和女性。五十六%是墨西哥裔美国人，12%是多米尼加裔美国人，14%是波多黎各裔美国人，18%是其他西班牙裔美国人。所有参与者均接受了冠状动脉钙化、胸主动脉钙化、颈动脉内膜中层厚度、踝臂指数、左心室质量和左心室大小的临床检查。墨西哥裔美国人的冠状动脉钙、胸主动脉钙和颈动脉内膜中层厚度水平最高，而波多黎各裔美国人的踝臂指数低于1.0和左心室质量水平最高。冠状动脉钙与年龄、性别和体重指数之间的关联程度在所有西班牙裔亚组中相似。然而，在不同的西班牙裔亚组中，冠状动脉钙与高血压、高胆固醇血症和吸烟之间的相关性在程度和意义上存在差异。其他亚临床CVD指标也存在该结果。这些结果表明，风险因素和西班牙裔亚组亚临床疾病的患病率或程度之间存在差异性关系。
In this study, the authors determined the prevalence and extent of cardiovascular disease (CVD) risk factors and subclinical CVD in four US Hispanic subgroups, as well as associations between the CVD risk factors and subclinical CVD in these groups. Participants were 1,437 Hispanic men and women enrolled in the Multi-Ethnic Study of Atherosclerosis in 2000-2002. Fifty-six percent were Mexican-American, 12% were Dominican-American, 14% were Puerto Rican-American, and 18% were Other Hispanic-American. All participants underwent clinical examinations for coronary artery calcium, thoracic aortic calcium, carotid intimal-medial thickness, ankle-brachial index, left ventricular mass, and left ventricular size. Mexican Americans had the highest levels of coronary artery calcium, thoracic aortic calcium, and carotid intimal-medial thickness, while Puerto Rican Americans had the highest prevalence of an ankle-brachial index less than 1.0 and levels of left ventricular mass. The magnitudes of the associations between coronary artery calcium and age, sex, and body mass index were similar across all Hispanic subgroups. However, there were differences in the magnitude and significance of the associations between coronary artery calcium and hypertension, hypercholesterolemia, and cigarette smoking among the different Hispanic subgroups. This finding was also present for the other subclinical CVD measures. These results suggest a differential relationship between risk factors and either prevalence or extent of subclinical disease by Hispanic subgroup.