Seasonality of Influenza in the Tropics: A Distinct Pattern in Northeastern Brazil
Seasonality of Influenza in the Tropics: A Distinct Pattern in Northeastern Brazil
复制标题
DOI：
10.4269/ajtmh.2009.81.180
复制
发表时间：
2009-07-01
影响因子：
3.3
通讯作者：
Siqueira, Marilda M.
中科院分区：
文献类型：
--
作者：
Moura, Fernanda E. A.;Perdigao, Anne C. B.;Siqueira, Marilda M.
流感疫情每年在世界范围内发生。流感的发病率在温带地区呈季节性，但对热带地区的流感季节性知之甚少。这项研究的目的是确定居住在巴西东北部福塔莱萨市的儿童中流感感染的流行率和季节性模式。对连续7年(2001-2007年)在医院门诊、急诊室和病房就诊的疑似急性呼吸道感染的儿童的鼻咽吸液进行了间接免疫荧光分析。有6.3%(234/3708)的标本检出流感病毒。以实验室为基础的监测数据显示，流感有明确的年度流行周期，高峰通常出现在雨季。在福塔莱萨，流感感染全年水平较低，但在雨季表现出明显的季节性增加。
Influenza epidemics occur worldwide annually. The incidence of influenza shows a seasonal pattern in temperate areas, but little is known about influenza seasonality in tropical regions. The objective of this study was to determine the prevalence and the seasonal pattern of influenza infections in children living in the city of Fortaleza in northeastern Brazil. An indirect immunofluorescence assay was performed on nasopharyngeal aspirates collected from children attending in ambulatories, emergency rooms, and wards of the Hospital Infantil Albert Sabin with suspicion of acute respiratory infection during 7 consecutive years (2001-2007). Influenza viruses were detected in 6.3% (234/3,708) of specimens. Laboratory-based surveillance data showed a clear annual epidemic cycle of influenza, with a peak usually occurring in the rainy periods. In Fortaleza, flu infections occurred at a low level throughout the year but exhibit a marked seasonal increase during the rainy season.