Hemodynamic and behavioral effects of angiotensin II in conscious sheep.

Hemodynamic and behavioral effects of angiotensin II in conscious sheep.
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血管紧张素 II 对清醒羊的血流动力学和行为影响。

DOI:
10.1152/ajpregu.1990.258.5.r1230
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发表时间:
1990
期刊:
The American journal of physiology
影响因子:
--
通讯作者:
Chimoskey,JE
Chimoskey,JE
中科院分区:
--
文献类型:
--
作者:
Breuhaus,BA;Chimoskey,JE

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材料与方法选用体重39 ~ 80 kg的成年母羊23只。这些羊被安置在单独的围栏里,在手术准备之前,它们被允许适应周围的环境和实验室人员。因为羊是群居动物,每个房间至少养了两只羊。这些条件确保了绵羊在实验过程中保持冷静和无压力。手术准备。14只羊用静脉滴注硫氨酰钠麻醉,插管,并保持在氟烷和氧气麻醉的手术平面上。患者背部仰卧,颈部准备无菌手术。
MATERIALS AND METHODSTwenty-three mature female sheep ranging in weight from 39 to 80 kg were used in this study. The sheep were housed in individual pens, and they were allowed to acclimate to their surroundings and to laboratory personnel before surgical preparation. Because sheep are flock animals, at least two sheep were kept in each room. These conditions ensured that the sheep were calm and unstressed during the experiments. Surgical preparation. Fourteen sheep were anesthetized with intravenous thiamylal sodium, intubated, and maintained in a surgical plane of anesthesia with halothane and oxygen. They were placed in dorsal recumbency and their necks were prepared for aseptic surgery.