Evaluation of ictal brain SPET using statistical parametric mapping in temporal lobe epilepsy
Evaluation of ictal brain SPET using statistical parametric mapping in temporal lobe epilepsy
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DOI：
10.1007/s002590000364
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发表时间：
2000-11-01
期刊：
影响因子：
--
通讯作者：
Kim, MJ
中科院分区：
文献类型：
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作者：
Lee, JD;Kim, HJ;Kim, MJ
使用统计参数映射（SPM）对脑图像进行基于体素的自动分析被认为是正电子发射断层扫描和功能磁共振成像中激活研究分析的标准方法。本研究旨在探讨SPM是否能提高颞叶癫痫（TLE）的颅脑单光子发射断层扫描（SPET）的诊断率。21例颞叶癫痫患者（年龄27.14±5.79岁）（右8例，左13例）手术后癫痫发作成功，9例正常受试者参与研究。采用SPM96软件对患者的初、间期脑SPET及正常对照组的基线SPET数据进行分析。将t统计量SPM(t)变换为具有不同阈值P的SPM(Z)
An automated voxel-based analysis of brain images using statistical parametric mapping (SPM) is accepted as a standard approach in the analysis of activation studies in positron emission tomography and functional magnetic resonance imaging. This study aimed to investigate whether or not SPM would increase the diagnostic yield of ictal brain single-photon emission tomography (SPET) in temporal lobe epilepsy (TLE). Twenty-one patients (age 27.14+/-5.79 years) with temporal lobe epilepsy (right in 8, left in 13) who had a successful seizure outcome after surgery and nine normal subjects were included in the study. The data of ictal and interictal brain SPET of the patients and baseline SPET of the normal control group were analysed using SPM96 software. The t statistic SPM(t) was transformed to SPM(Z) with various thresholds of P