Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet‐light‐cured paint, and bisphenol A in dental composite resin
Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet‐light‐cured paint, and bisphenol A in dental composite resin
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紫外光固化涂料中的环氧二丙烯酸酯和牙科复合树脂中的双酚A引起的职业过敏性接触性皮炎
作者：
R. Jolanki;L. Kanerva;T. Estlander
由环氧二甲基丙烯酸酯或双酚A引起的过敏性接触性皮炎（ACD）是罕见的。这里报告了2例这样的病例。一名牙科助理因使用环氧二甲基丙烯酸酯为基础的拒绝复合树脂（DCR）产品中含有双酚A引起过敏性接触性皮炎（ACD）。通过对双酚A和2个dcr的过敏贴反应证实了接触性过敏。对引起过敏反应的ocr进行分析，检测到双酚A含量为0.014 ~ 0.015%。牙科复合树脂中双酚A引起的职业性ACD尚未见报道。另一名患者是一名油漆工厂的工序工人。他被环氧二丙烯酸酯、2.2 -双[4 -（2 -羟基- 3 -丙烯氧基丙氧基）苯]-丙烷（bis - GA）和其他含有在紫外光固化涂料原料中的丙烯酸酯化合物敏化。环氧二丙烯酸酯对pet的过敏斑贴试验反应低至0.016%。他对其他几种丙烯酸酯化合物也有过敏反应。2 -丙烯酸羟丙酯、2 -丙烯酸羟丙酯、1,4 -丁二醇二丙烯酸酯、1,6 -己二醇二丙烯酸酯、二丙烯酸二乙二醇二丙烯酸酯、三乙二醇二丙烯酸酯和三丙二醇二丙烯酸酯，表明交叉和/或同时敏化。
Allergic contact dermatitis (ACD) caused by epoxy di(meth)acrylates or bisphenol A is rare. Here 2 such cases are reported. A dental assistant had allergic contact dermatitis (ACD) caused by bisphenol A contained in denial composite resin (DCR) products based on epoxy dimethacrylate. The contact allergy was verified by allergic patch lest reactions to bisphenol A and 2 DCRs. The OCRs giving allergic reactions were analyzed, and 0.014–0.015% of bisphenol A was detected. Occupational ACD caused by bisphenol A in dental composite resins has not been described before. The other patient was a male process worker in a paint factory. He was sensitized by an epoxy diacrylate, 2.2‐bis[4‐(2‐hydroxy‐3‐acryloxypropoxy)pheny]‐propane (BIS‐GA), and other acrylate compounds contained in raw materials of ultraviolet‐light‐curable paint. The epoxy diacrylate gave an allergic patch test reaction down to 0.016% in pet. He also had an allergic patch lest reaction to several other acrylate compounds. 2‐hydroxypropyl acrylate, 2‐hydroxypropyl acrylate, 1,4‐butanediol diacrylate, 1,6‐hexanediol diacrylate, diethyleneglycol diacrylate, triethylene glycol diacrylate, and tripropylene glycol diacrylate, indicating cross and/or concomitant sensitization.
双酚 A 实验性光过敏性接触性皮炎。
影响因子：
3.6
作者：
MaguireJr,HC
通讯作者：
MaguireJr,HC