Incidence and mortality of hip fracture among the elderly population in South Korea: a population-based study using the national health insurance claims data.

Incidence and mortality of hip fracture among the elderly population in South Korea: a population-based study using the national health insurance claims data.
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DOI:
10.1186/1471-2458-10-230
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发表时间:
2010-05-04
期刊:
影响因子:
4.5
通讯作者:
Park SE
Park SE
中科院分区:
医学2区
文献类型:
--
作者:
Kang HY;Yang KH;Kim YN;Moon SH;Choi WJ;Kang DR;Park SE

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在韩国,缺乏骨质疏松性髋部骨折的流行病学信息阻碍了对骨质疏松症的预防或治疗措施的发展。我们进行了一项基于人群的研究,以估计髋部骨折的年发病率。此外,我们还研究了与韩国老年人骨折后死亡率相关的因素,以评估骨质疏松症对我们社会的影响,并确定高危人群。韩国国民健康保险(NHI)索赔数据库用于确定髋部骨折的发生率,髋部骨折定义为2003年期间有髋部骨折诊断和髋部骨折相关手术索赔记录的患者。2003年之前的6个月被设定为“窗口期”,这样,只有在窗口期之后观察到患者的首次骨折记录时,才将其定义为事件病例。考克斯的比例风险模型被用来调查生存时间和基线病人和提供者的特性之间的关系,从全民健康保险的数据。50岁以上需要手术的髋部骨折的年龄标准化年发病率为每100 000名妇女146.38人,每100 000名男子61.72人,男女比例为2.37。1年死亡率为16.55%,是该年龄组一般人口死亡率(5.8%)的2.85倍。对于男性和社会经济地位较低、居住在首都以外的地方、骨折后未接受抗骨质疏松药物治疗或在综合医院或三级医院等更先进的医院接受骨关节相关手术的人,骨折后一年死亡的风险明显较高。这项全国流行病学研究将有助于提高老年人对骨质疏松性髋部骨折的认识,并有望激励公共卫生政策制定者制定有效的国家预防骨质疏松症战略,以预防髋部骨折。
The lack of epidemiologic information on osteoporotic hip fractures hampers the development of preventive or curative measures against osteoporosis in South Korea. We conducted a population-based study to estimate the annual incidence of hip fractures. Also, we examined factors associated with post-fracture mortality among Korean elderly to evaluate the impact of osteoporosis on our society and to identify high-risk populations. The Korean National Health Insurance (NHI) claims database was used to identify the incidence of hip fractures, defined as patients having a claim record with a diagnosis of hip fracture and a hip fracture-related operation during 2003. The 6-month period prior to 2003 was set as a 'window period,' such that patients were defined as incident cases only if their first record of fracture was observed after the window period. Cox's proportional hazards model was used to investigate the relationship between survival time and baseline patient and provider characteristics available from the NHI data. The age-standardized annual incidence rate of hip fractures requiring operation over 50 years of age was 146.38 per 100,000 women and 61.72 per 100,000 men, yielding a female to male ratio of 2.37. The 1-year mortality was 16.55%, which is 2.85 times higher than the mortality rate for the general population (5.8%) in this age group. The risk of post-fracture mortality at one year is significantly higher for males and for persons having lower socioeconomic status, living in places other than the capital city, not taking anti-osteoporosis pharmacologic therapy following fracture, or receiving fracture-associated operations from more advanced hospitals such as general or tertiary hospitals. This national epidemiological study will help raise awareness of osteoporotic hip fractures among the elderly population and hopefully motivate public health policy makers to develop effective national prevention strategies against osteoporosis to prevent hip fractures.
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