Human Brain Atlas: For High-Resolution Functional and Anatomical Mapping
Human Brain Atlas: For High-Resolution Functional and Anatomical Mapping
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DOI：
10.1002/hbm.460010303
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发表时间：
1993-01-01
影响因子：
4.8
通讯作者：
Zilles, K.
中科院分区：
文献类型：
--
作者：
Roland, P. E.;Graufelds, C. J.;Zilles, K.
我们推出了新的计算机化人脑图谱 (HBA)，用于人脑的解剖和功能绘图研究。 HBA 基于正常受试者的许多高分辨率磁共振图像，并提供人脑解剖结构的平均形状和位置的持续更新。这些结构可以通过应用于 3D 图片中任何位置的线性和非线性全局和局部变换来变换，以适应个体大脑的解剖结构，通过重新格式化，将其转换为高分辨率标准解剖格式。 HBA 减少解剖变异的能力是通过随机选择 27 名年轻正常男性志愿者大脑中的解剖标志来评估的，这些志愿者与选择标准大脑的志愿者不同。即使仅基于标准的大脑表面和中央结构，HBA 也可以将个体间的解剖差异降低到个体大脑左右半球之间结构位置差异的水平。
We present the new computerized Human Brain Atlas (HBA) for anatomical and functional mapping studies of the human brain. The HBA is based on many high-resolution magnetic resonance images of normal subjects and provides continuous updating of the mean shape and position of anatomical structures of the human brain. The structures are transformable by linear and nonlinear global and local transformations applied anywhere in 3-D pictures to fit the anatomical structures of individual brains, which, by reformatting, are transformed into a high-resolution standard anatomical format. The power of the HBA to reduce anatomical variations was evaluated on a randomized selection of anatomical landmarks in brains of 27 young normal male volunteers who were different from those on whom the standard brain was selected. The HBA, even when based only on standard brain surface and central structures, reduced interindividual anatomical variance to the level of the variance in structure position between the right and left hemisphere in individual brains.