Phase-amplitude coupling between theta and gamma oscillations during nociception in rat electroencephalography
Phase-amplitude coupling between theta and gamma oscillations during nociception in rat electroencephalography
复制标题
大鼠脑电图伤害感受期间 theta 和 gamma 振荡之间的相位幅度耦合
DOI：
10.1016/j.neulet.2011.05.037
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发表时间：
2011-07-20
影响因子：
2.5
通讯作者：
Wan, You
中科院分区：
文献类型：
--
作者：
Wang, Jing;Li, Duan;Wan, You
在脑电图（EEG）研究中，γ振荡参与了疼痛加工，θ振荡也参与了疼痛加工。此外，θ总是调制γ活动的相位振幅耦合的事件相关的振荡。在疼痛过程中，θ波是否通过相位-振幅耦合来调制γ波是一个值得关注的问题。在本研究中，使用大鼠激光伤害性刺激后的EEG，我们研究了γ活动和θ和γ之间的相位振幅耦合。发现在伤害性刺激开始后200 ms开始诱导伽马功率增加。此外，theta相位和伽玛振幅之间的显着耦合被发现后，额叶和顶叶区的伤害性刺激。我们的研究结果首次表明，θ和γ之间的耦合参与伤害性感受处理。(C)2011爱思唯尔爱尔兰有限公司保留所有权利。
In electroencephalography (EEG) study, gamma oscillations were reported to participate in pain processing: theta oscillations were also involved in pain processing. Moreover, theta always modulated gamma activity by phase-amplitude coupling in event-related oscillations. Whether theta modulate gamma by phase-amplitude coupling in pain processing is of interest. In the present study, using EEG of rats after laser nociceptive stimulation, we investigated gamma activity and phase-amplitude coupling between theta and gamma. It was found that induced gamma power increased starting 200 ms after nociceptive stimulation onset. Moreover, significant coupling between theta phase and gamma amplitude was found over frontal and parietal region after nociceptive stimulation. Our results for the first time suggest that coupling between theta and gamma is involved in nociception processing. (C) 2011 Elsevier Ireland Ltd. All rights reserved.