Socio-economic status influences the relationship between obesity and antenatal depression: Data from a prospective cohort study
Socio-economic status influences the relationship between obesity and antenatal depression: Data from a prospective cohort study
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DOI：
10.1016/j.jad.2016.05.061
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发表时间：
2016-09-15
影响因子：
6.6
通讯作者：
Howard, L. M.
中科院分区：
文献类型：
--
作者：
Molyneaux, E.;Pasupathy, D.;Howard, L. M.
背景：肥胖与产前抑郁风险增加有关，但对这种关系知之甚少。本研究测试是否社会经济地位（SES）影响肥胖和产前depress.Methods之间的关系：数据取自筛查妊娠终点（SCOPE）队列。根据妊娠15 +/- 1周时测量的身高和体重计算BMI。体重不足的妇女被排除在外。SES由自我报告的家庭收入（围绕中位数进行二分法：低SES <45，000;磅高SES > 45，000）磅表示。产前抑郁定义为爱丁堡产后抑郁量表在15 +/- 1和20 +/- 1周的妊娠期得分>= 13，以确定持续升高的抑郁症状。结果：5522名妇女被纳入这些分析，5.5%的持续升高的产前抑郁症状。SES和BMI对产前抑郁症的风险有显著的交互作用（p=0.042）。在高SES妇女中，肥胖妇女产前抑郁的几率大约是正常体重对照妇女的两倍（AOR 2.11，95%CI 1.16-3.83，p=0.014，调整混杂因素）。在低社会经济地位的妇女中，肥胖和产前抑郁症之间没有联系。在敏感性分析中，相互作用效应对SES的替代指标是稳健的。局限性：1）产前抑郁症进行了评估与自我报告的筛选措施;和2）潜在的介质，如耻辱和身体形象差不能examined.Conclusions：肥胖只与高SES妇女在此样本中产前抑郁症的风险增加。医疗保健专业人员应该意识到，产前抑郁症在低SES女性中更常见，无论BMI类别如何。(C)2016作者由爱思唯尔公司出版。这是一篇开放获取的文章，使用CC BY许可证（http：//creativecommons.org/licenses/by/4.0/）。
Background: Obesity has been associated with increased risk of antenatal depression, but little is known about this relationship. This study tested whether socio-economic status (SES) influences the relationship between obesity and antenatal depression.Methods: Data were taken from the Screening for Pregnancy Endpoints (SCOPE) cohort. BMI was calculated from measured height and weight at 15 +/- 1 weeks' gestation. Underweight women were excluded. SES was indicated by self-reported household income (dichotomised around the median: low SES < 45,000; pound high SES > 45,000) pound. Antenatal depression was defined as scoring >= 13 on the Edinburgh Postnatal Depression Scale at both 15 +/- 1 and 20 +/- 1 weeks' gestation, to identify persistently elevated symptoms of depression.Results: Five thousand five hundred and twenty two women were included in these analyses and 5.5% had persistently elevated antenatal depression symptoms. There was a significant interaction between SES and BMI on the risk of antenatal depression (p=0.042). Among high SES women, obese women had approximately double the odds of antenatal depression than normal weight controls (AOR 2.11, 95%Cl 1.16-3.83, p=0.014, adjusted for confounders). Among low SES women there was no association between obesity and antenatal depression. The interaction effect was robust to alternative indicators of SES in sensitivity analyses. Limitations: 1) Antenatal depression was assessed with a self-reported screening measure; and 2) potential mediators such as stigma and poor body-image could not be examined.Conclusions: Obesity was only associated with increased risk of antenatal depression among high SES women in this sample. Healthcare professionals should be aware that antenatal depression is more common among low SES women, regardless of BMI category. (C) 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).