Risk factors for surgical site infection after malignant bone tumor resection and reconstruction
Risk factors for surgical site infection after malignant bone tumor resection and reconstruction
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DOI：
10.1186/s12885-019-5270-8
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发表时间：
2019-01-08
期刊：
影响因子：
3.8
通讯作者：
Tsuchiya, Hiroyuki
中科院分区：
文献类型：
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作者：
Miwa, Shinji;Shirai, Toshiharu;Tsuchiya, Hiroyuki
植入物的使用是恶性骨肿瘤切除术后手术部位感染的危险因素之一。我们开发了一种在钛种植体表面涂覆碘以防止感染的新技术。本研究旨在探讨恶性骨肿瘤切除术后SSI的危险因素，评价碘包被植入物预防SSI的效果。结果SSI发生率为10.9%(33/302个肿瘤)。骨盆骨肿瘤(OR：4.8，95%CI：1.8~13.4)和手术时间5h(OR：3.4，95%CI：1.2~9.6)是SSI的独立危险因素。结论骨盆骨肿瘤和手术时间长是恶性骨肿瘤切除重建术后SSI的危险因素，碘包被有望成为预防SSI的一种有效方法。
BackgroundUse of an implant is one of the risk factors for surgical site infection (SSI) after malignant bone tumor resection. We developed a new technique of coating titanium implant surfaces with iodine to prevent infection. In this retrospective study, we investigated the risk factors for SSI after malignant bone tumor resection and to evaluate the efficacy of iodine-coated implants for preventing SSI.MethodsData from 302 patients with malignant bone tumors who underwent malignant bone tumor resection and reconstruction were reviewed. Univariate analyses were performed, followed by multivariate analysis to identify risk factors for SSI based on the treatment and clinical characteristics.ResultsThe frequency of SSI was 10.9% (33/302 tumors). Pelvic bone tumor (OR: 4.8, 95% CI: 1.8-13.4) and an operative time5h (OR: 3.4, 95% CI: 1.2-9.6) were independent risk factors for SSI. An iodine-coated implant significantly decreased the risk of SSI (OR: 0.3, 95% CI: 0.1-0.9).ConclusionThe present data indicate that pelvic bone tumor and long operative time are risk factors for SSI after malignant bone tumor resection and reconstruction, and that iodine coating may be a promising technique for preventing SSI.