Progress in Measurement Instruments for Acute and Chronic Gout Studies
Progress in Measurement Instruments for Acute and Chronic Gout Studies
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DOI：
10.3899/jrheum.090371
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发表时间：
2009-10-01
影响因子：
3.9
通讯作者：
Schumacher, H. Ralph
中科院分区：
文献类型：
--
作者：
Grainger, Rebecca;Taylor, William J.;Schumacher, H. Ralph
共识练习已经确定并优先考虑了急性和慢性痛风研究的测量领域。与此同时，对许多这些领域的测量仪器的技术特性进行了评估，其主要目标是在OMERACT真理、鉴别和可行性过滤器的背景下考虑这些仪器。这些数据在痛风研讨会、分组小组和痛风小组非正式会议上进行了介绍和讨论。在急性痛风中，用于疼痛、关节肿胀的器械。关节压痛，病人和医生的整体评估已被评估。在慢性痛风中，一些验证练习已经在血清尿酸、痛风素测量、健康相关生活质量（HRQOL）领域的仪器中进行。在OMERACT 9的投票中，医疗结果研究简表36被认可为衡量HRQOL的有效工具。风石的测量方法被认为已经满足了OMERACT过滤器的一些标准，但这些需要进一步的工作，特别是在较短时间内变化的敏感性方面。未来研究的重点包括测量急性痛风的关节炎症和急性和慢性痛风的残疾。[J] .风湿病杂志2009；36:2346-55;doi: 10.3899/ jrheumat.090371]
Consensus exercises have identified and prioritized domains of measurement for studies in acute and chronic gout. In parallel, the technical properties of instruments for measurement in many of these domains have been assessed, with the main objective to consider the instruments in the context of the OMERACT filter of truth, discrimination, and feasibility. These data were presented and discussed at OMERACT 9 in the Gout workshop, in breakout groups, and at informal meetings of the gout group. In acute gout, instruments for domains of pain, joint swelling. joint tenderness, and patient and physician global assessment have been assessed. In chronic gout, some validation exercises have been performed in instruments for domains serum urate, tophus measurement, health-related quality of life (HRQOL). In voting at OMERACT 9, the Medical Outcomes Study Short-Form 36 was endorsed as a valid instrument for measurement of HRQOL. Methods of tophus measurement were considered to have met some criteria of the OMERACT filter, but these require further work, particularly regarding sensitivity to change over shorter time periods. Priorities for future research include measurement of joint inflammation in acute gout and disability in acute and chronic gout. (J Rheumatol 2009;36:2346-55; doi: 10.3899/jrheum.090371)