Rectal cancer: Incidence of pulmonary metastases on thoracic CT and correlation with T staging
Rectal cancer: Incidence of pulmonary metastases on thoracic CT and correlation with T staging
复制标题
DOI：
10.1097/rct.0b013e318032e8c9
复制
发表时间：
2007-07-01
影响因子：
1.3
通讯作者：
Bankart, Michael J. G.
中科院分区：
文献类型：
--
作者：
Kirke, Rathy;Rajesh, Arumugam;Bankart, Michael J. G.
目的：本研究的目的是评估胸部计算机断层扫描检测到的直肠癌患者肺转移的发生率，并评估肺转移的发生率和直肠tumor.Materials and Methods的阶段之间的关联：五十六连续患者被诊断为直肠癌超过22个月的时间被列入研究。这些患者进行了局部肿瘤分期与盆腔磁共振成像和分期计算机断层扫描的胸部和上腹部后立即磁共振成像。两名放射科医生回顾性审查了对这些患者进行的所有胸部影像学检查，以确定是否存在转移。肺实质结节（单个结节大于或等于1 cm，多个结节大于或等于0.5 cm）伴软组织成分且肺和纵隔窗上无钙化，则认为存在转移。结果：在56例患者中，10例（17.9%）在CT上有肺转移的证据。在56名患者中，有3名患者为T1期，24名为T2期，26名为T3期，3名为T4期肿瘤。在这10例患者中，1例为T2期肿瘤，7例为T3期肿瘤，2例为T4期肿瘤。使用精确的Logistic回归统计分析显示，获得肺转移的几率是一个增加的功能肿瘤gradient.Conclusions：有一个高发病率的直肠癌患者肺转移，胸部计算机断层扫描应作为一个分期协议的一部分，在所有患者的任何形式的治疗计划。T分期越高，肺转移的发生率越高。
Purpose: The aim of the study was to evaluate the incidence of pulmonary metastases detected on thoracic computed tomography in patients with rectal cancer and assess the association between the incidence of pulmonary metastases and the stage of the rectal tumor.Materials and Methods: Fifty-six consecutive patients who were diagnosed with rectal cancer over a 22-month period were included in the study. These patients had local tumor staging with a pelvic magnetic resonance imaging and staging computed tomographic scan of the chest and upper abdomen immediately after the magnetic resonance imaging. Two radiologists retrospectively reviewed all the thoracic imaging performed on these patients for the presence of metastases. The presence of a parenchymal lung nodule (greater than or equal to 1 cm if single and 0.5 cm if multiple) with a soft tissue component without calcification on lung and mediastinal window settings was considered positive for the presence of metastasis. All other patients were considered as not having any lung metastases.Results: Of the 56 patients, 10 (17.9%) had evidence of pulmonary metastases on computed tomography. Of the 56 patients, there were 3 patients with stage T1, 24 with T2, 26 with T3, and 3 with stage T4 tumors. Of these 10 patients, 1 had a stage T2 tumor, 7 had T3, and 2 had stage T4 tumors. Statistical analysis using exact logistic regression showed the odds of getting lung metastases is an increasing function of tumor grade.Conclusions: There is a high incidence of lung metastases in patients with rectal cancer, and thoracic computed tomographic scanning should be performed as part of a staging protocol in all patients before any form of treatment is planned. There is a higher incidence of lung metastases with higher T stage.