Temperature sensitivity control of alkylamide-terminated poly(amidoamine) dendrimers induced by guest molecule binding
Temperature sensitivity control of alkylamide-terminated poly(amidoamine) dendrimers induced by guest molecule binding
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DOI：
10.1021/ja0711718
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发表时间：
2007-06-13
影响因子：
15
通讯作者：
Harada, Atsushi
中科院分区：
文献类型：
--
作者：
Kono, Kenji;Miyoshi, Takuma;Harada, Atsushi
我们研究了虎红（RB）与烷基酰胺封端的PAMAM G5树枝状聚合物的结合对其温度敏感性的影响。的浊点的水溶液中的异丁酰胺终止的树枝状大分子的RB分子结合到树枝状大分子的量的增加而降低。丙酰胺封端的树枝状聚合物，这是根本上的温度不敏感，也表现出一个浊点后，绑定的RB。结果表明，与客体分子的络合作用可能是控制树枝状大分子温度敏感性甚至温度增敏的有效途径。
We examined the effect of binding of rose bengal (RB) to alkylamide-terminated PAMAM G5 dendrimers on their temperature-sensitive properties. The cloud point of aqueous solutions of the isobutyramide-terminated dendrimer decreased with increasing amount of RB molecules bound to the dendrimer. The propylamide-terminated dendrimer, which is fundamentally temperature-insensitive, also exhibited a cloud point after binding of RB. Results indicate that complexation with guest molecules might be an efficient approach for control of temperature sensitivity or even temperature sensitization of dendrimers.