QUALITY-OF-LIFE IN PATIENTS WITH UPPER GASTROINTESTINAL SYMPTOMS - AN IMPROVED EVALUATION OF TREATMENT REGIMENS
QUALITY-OF-LIFE IN PATIENTS WITH UPPER GASTROINTESTINAL SYMPTOMS - AN IMPROVED EVALUATION OF TREATMENT REGIMENS
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DOI：
10.3109/00365529309098272
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发表时间：
1993-08-01
影响因子：
1.9
通讯作者：
WIKLUND, I
中科院分区：
文献类型：
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作者：
DIMENAS, E;GLISE, H;WIKLUND, I
人们对医学中的生活质量（QoL）测量越来越感兴趣。与内窥镜检查记录的愈合率等客观变量一起，这被认为是评价上消化道疾病患者治疗方案的更好依据。本文提出了一种评估上消化道症状患者生活质量的策略。生活质量评价基于一系列问卷调查，涵盖生活的一般和具体方面。总体幸福感采用心理总体幸福感指数（PGWB）进行评估，主观症状采用两种特定的问卷，即胃肠道症状评定量表（GSRS）和溃疡性食管炎主观症状量表（UESS）。对146例门诊疑似消化性溃疡患者进行了临床应用研究。最初，患者报告了较低程度的总体幸福感，但在4周内恢复到正常人群中的数值。GSRS和UESS的内部一致性，结构效度和检测变化的能力方面的评价表明，他们是令人满意的。心理测量文件的措施表明，他们可以提供可靠的和临床有效的信息时，用于评价上消化道疾病的药物治疗。然而，需要进一步的方法文件，以建立一个普遍接受的生活质量评估胃肠病学。
There is growing interest in measuring quality of life (QoL) in medicine. Together with objective variables such as healing rate, as recorded with endoscopy, this is believed to give a better basis for evaluation of treatment regimens in patients with upper gastrointestinal diseases. A strategy for the assessment of QoL in patients with upper gastrointestinal symptoms is presented here. The QoL evaluation was based on a battery of questionnaires, covering both general and specific aspects of life. General well-being was evaluated with the Psychological General Well-being Index (PGWB), and subjective symptoms with two specific questionnaires, the Gastrointestinal Symptom Rating Scale (GSRS) and the Ulcus Esophagitis Subjective Symptoms Scale (UESS). This new strategy was applied clinically in a study including 146 outpatients with suspected peptic ulcer. Initially, the patients reported a low degree of general well-being as evaluated with the PGWB, but the values returned to those found in normal populations within 4 weeks. Evaluation of the GSRS and UESS with regard to internal consistency, construct validity, and the ability to detect changes showed them to be satisfactory. The psychometric documentation of the measures indicates that they may give reliable and clinically valid information when used for evaluation of medical treatments in upper gastrointestinal disease. Further documentation of the methods is, however, needed to establish a generally acceptable QoL assessment in gastroenterology.