Altered smell and taste: anosmia, parosmia and the impact of long Covid-19

Altered smell and taste: anosmia, parosmia and the impact of long Covid-19
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嗅觉和味觉改变:嗅觉缺失、嗅觉异常以及长期 Covid-19 的影响

DOI:
10.1101/2020.11.26.20239152
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发表时间:
2020
期刊:
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影响因子:
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通讯作者:
Burges Watson D
Burges Watson D
中科院分区:
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文献类型:
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作者:
Burges Watson D

文献摘要

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背景定性嗅觉(嗅觉)功能障碍是病毒感染后疾病的常见副作用,已知会影响生活质量和健康状况。越来越多的证据表明,味觉和嗅觉丧失是新冠肺炎的常见症状,在首次感染后可能会出现并持续很长时间。这项研究的目的是记录新冠肺炎帖子对味觉和嗅觉的影响。方法从2020年3月24日至9月30日,我们对9,000名新冠肺炎用户生成的文本进行了探索性的主题分析。结果参与者报告难以解释和管理味觉和嗅觉的改变;缺乏人际和专业的解释或支持;饮食改变;食欲下降,体重变化;对食物、饮食和社交的快感丧失;亲密关系改变以及与自我和他人的关系改变。结论我们的研究结果提示,新冠肺炎的味道和气味改变可能会严重扰乱日常生活,影响心理健康、身体健康、人际关系和自我感觉。更具体地说,参与者报告了与以下方面有关的影响:吃和准备食物的欲望和能力降低;体重增加、体重减轻和营养不足;情绪健康;职业实践;亲密关系和社会纽带;以及人们对现实和他们自己的破坏。我们的发现将为进一步的研究提供信息,并为从事Long Covid工作的卫生保健专业人员的培训、评估和治疗实践提供建议。
Background Qualitative olfactory (smell) dysfunctions are a common side effect of post-viral illness and known to impact quality of life and health status. Evidence is emerging that taste and smell loss are common symptoms of Covid-19 that may emerge and persist long after initial infection. The aim of the present study was to document the impact of post Covid-19 alterations to taste and smell. Methods We conducted exploratory thematic analysis of user-generated text from 9000 users of the AbScent Covid-19 Smell and Taste Loss moderated Facebook support group from March 24 to 30th September 2020. Results Participants reported difficulty explaining and managing an altered sense of taste and smell; a lack of interpersonal and professional explanation or support; altered eating; appetite loss, weight change; loss of pleasure in food, eating and social engagement; altered intimacy and an altered relationship to self and others. Conclusions Our findings suggest altered taste and smell with Covid-19 may lead to severe disruption to daily living that impacts on psychological well-being, physical health, relationships and sense of self. More specifically, participants reported impacts that related to reduced desire and ability to eat and prepare food; weight gain, weight loss and nutritional insufficiency; emotional wellbeing; professional practice; intimacy and social bonding; and the disruption of people’s sense of reality and themselves. Our findings should inform further research and suggest areas for the training, assessment and treatment practices of health care professionals working with long Covid.