Biliary strictures after liver transplantation: Clinical picture, correlates and outcomes
Biliary strictures after liver transplantation: Clinical picture, correlates and outcomes
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DOI：
10.1111/j.1440-1746.1996.tb00005.x
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发表时间：
1996-01-01
影响因子：
4.1
通讯作者：
McCaughan, GW
中科院分区：
文献类型：
--
作者：
Feller, RB;Waugh, RC;McCaughan, GW
我们回顾性检查了 154 名成人，以确定肝移植后胆管狭窄的频率、部位和诱发因素，以及其治疗和临床结果。 20 名患者 (12.5%) 被确定患有胆道狭窄； 16 例为非吻合，4 例为吻合狭窄。从移植到狭窄诊断的中位时间为 17 周（范围 3-366）。 16 例非吻合口狭窄中，6 例为肝内狭窄，8 例为肝门狭窄，2 例为肝外狭窄（供体胆管）。对照组（n = 32）在指示病例之前和之后立即进行移植的患者用于检查非吻合口狭窄患者的相关性。在非吻合指数病例诊断时，以下情况的发生率较高：(i) 胆泥（63% vs 0%；P
We retrospectively examined 154 adults to ascertain the frequency, site of and pre-disposing factors for biliary strictures after liver transplantation, as well as their management and clinical outcome. Twenty patients (12.5%) were identified with biliary strictures; 16 were non-anastomotic and four were anastomotic strictures. The median time from transplantation to stricture diagnosis was 17 weeks (range 3-366). Of the 16 non-anastomotic strictures, six were intrahepatic, eight hilar and two extrahepatic (donor bile duct). A control group (n = 32) of patients transplanted immediately before and after index cases was used to examine for correlates in patients with non-anastomotic strictures. At the time of diagnosis in the non-anastomotic index cases, there was a higher incidence of: (i) biliary sludge (63 vs 0%; P