Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence
Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence
复制标题
从cDNA序列推导出加州鱼雷乙酰胆碱受体α亚基前体的一级结构
作者：
M. Noda;Hideo Takahashi;T. Tanabe;M. Toyosato;Y. Furutani;T. Hirose;M. Asai;S. Inayama;T. Miyata;S. Numa
克隆了编码乙酰胆碱受体α亚单位前体的加利福尼亚鱼雷电浆mRNA的DNA序列。测序结果表明，其前体由461个氨基酸组成，其中包括24个氨基酸的前肽。讨论了乙酰胆碱结合的可能部位和α亚单位分子上的抗原决定簇。
DNA sequences complementary to the Torpedo californica electroplax mRNA coding for the α-subunit precursor of the acetylcholine receptor were cloned. The nucleotide sequence of the cloned cDNA indicates that the precursor consists of 461 amino acids including a prepeptide of 24 amino acids. Possible sites for acetylcholine binding and antigenic determinants on the α-subunit molecule are discussed.
DOI：
10.1073/pnas.79.1.188
发表时间：
1982-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
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作者：
TZARTOS, SJ;SEYBOLD, ME;LINDSTROM, JM
通讯作者：
LINDSTROM, JM