A LARGE DELETION OF LONG ARM OF CHROMOSOME NO 4 IN A CHILD WITH LIMB ABNORMALITIES
A LARGE DELETION OF LONG ARM OF CHROMOSOME NO 4 IN A CHILD WITH LIMB ABNORMALITIES
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DOI：
10.1136/adc.42.224.428
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发表时间：
1967-01-01
影响因子：
5.2
通讯作者：
DELANEY, MJ
中科院分区：
文献类型：
--
作者：
OCKEY, CH;FELDMAN, GV;DELANEY, MJ
A large chromosome deletion has been observed in a 3 1/2-month-old boy. The child showed abnormalities of the left upper limb, a congenital heart defect and dislocation of the hip. Quantitative morphological and autoradiographical analysis showed that a segment was deleted from the long arm of chromosome No. 4, amounting to 23 %. This deletion and most of those already reported involve segments containing a high proportion of late-labelling DNA and, therefore, presumably genetically inactive material. These represent only a small percentage of the actual deletions occurring.
