Er:YAG laser resurfacing for inoperable medium‐sized facial congenital melanocytic naevi in children
Er:YAG laser resurfacing for inoperable medium‐sized facial congenital melanocytic naevi in children
复制标题
Er:YAG激光换肤治疗无法手术的儿童面部中型先天性黑素细胞痣
DOI：
10.1111/j.1365-2230.2006.02286.x
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发表时间：
2007
影响因子：
4.1
通讯作者：
S. Lanigan
中科院分区：
文献类型：
--
作者：
S. Rajpar;A. Abdullah;S. Lanigan
先天性黑色素细胞痣（CMN）可引起严重的心理社会疾病，特别是如果它们位于视觉暴露区域。首选的治疗方法是手术切除，但并非所有病变都适合手术切除，因为解剖位置可能妨碍美学和功能重建。三名儿童无法手术的面部CMN治疗Er：YAG表面置换术在全身麻醉下。两名儿童为菲茨帕特里克皮肤II型，一名儿童为皮肤VI型。每隔4-9个月进行一次治疗。该手术在所有三例病例中均实现了显著的变浅和变薄，没有瘢痕或色素沉着。一名儿童在一次治疗区域发生单纯疱疹感染，经口服阿昔洛韦治疗，未导致瘢痕形成或妨碍进一步治疗。我们的结论是，Er：YAG激光换肤是有效的CMN，即使在较深的皮肤类型。副作用的发生率很低，尽管需要重复治疗。
Congenital melanocytic naevi (CMN) can cause significant psychosocial morbidity, especially if they are in visually exposed areas. The preferred treatment is surgical excision, though not all lesions are amenable to this because anatomical location may preclude aesthetic and functional reconstruction. Three children with inoperable facial CMN were treated with Er:YAG resurfacing under general anaesthetic. Two children were Fitzpatrick skin type II, and one child was skin type VI. Treatment was performed at 4–9‐monthly intervals. The procedure achieved significant lightening and thinning in all three cases, without scarring or dyspigmentation. One child developed herpes simplex infection in the treated area on one occasion, which was managed with oral aciclovir, and did not lead to scarring or preclude further treatment. We conclude that Er:YAG laser resurfacing is effective for CMN, even in darker skin types. The incidence of side‐effects is low, although repeated treatment is necessary.