PLASMA ADRENOCORTICOTROPIN AND CORTISOL RESPONSES TO BRIEF HIGH-INTENSITY EXERCISE IN HUMANS
PLASMA ADRENOCORTICOTROPIN AND CORTISOL RESPONSES TO BRIEF HIGH-INTENSITY EXERCISE IN HUMANS
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DOI：
10.1152/jappl.1986.61.4.1337
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发表时间：
1986-10-01
影响因子：
3.3
通讯作者：
HODGDON, JA
中科院分区：
文献类型：
--
作者：
BUONO, MJ;YEAGER, JE;HODGDON, JA
本研究的目的是检查短暂的高强度运动后血浆皮质醇和促肾上腺皮质激素 (ACTH) 的水平。每个受试者 (n = 6) 在自行车测力计上以最大摄氧量的 120% 进行 1 分钟的锻炼。在休息时、运动后立即以及运动后 5、15 和 30 分钟采集血样。平均 (.+-. SE) 血浆 ACTH 水平从 2.2 .+- 显着增加 (P < 0.05)。静态时为 0.04 pmol/l 至 6.2 .+-。运动后立即达到 1.7 pmol/l。平均 (.+-. SE) 血浆皮质醇水平从 0.40 .+- 显着增加。静止状态下为 0.04 .mu.mol/l 至 0.52 .+-。运动后 15 分钟为 0.04 .mu.mol/l。这些数据表明，短暂的高强度运动会导致血浆皮质醇和 ACTH 水平显着增加。此外，两种激素之间的时间顺序表明，短暂的高强度运动后血浆皮质醇水平的增加是肾上腺皮质中ACTH诱导的类固醇生成的结果。
The purpose of this study is to examine plasma cortisol and adrenocorticotropin (ACTH) levels following a brief high-intensity bout of exericse. Each subject (n = 6) performed a 1-min bout of exercise on a cycle ergometer at 120% of his maximum O2 uptake. Blood samples were collected at rest, immediately following the exercise bout, and at 5, 15, and 30 min postexercise. Mean (.+-. SE) plasma ACTH levels increased significantly (P < 0.05) from 2.2 .+-. 0.04 pmol/l at rest to 6.2 .+-. 1.7 pmol/l immediately following exercise. Mean (.+-. SE) plasma cortisol levels increased significantly from 0.40 .+-. 0.04 .mu.mol/l at rest to 0.52 .+-. 0.04 .mu.mol/l at 15 min postexercise. These data show that brief high-intensity exercise results in significant increases in plasma cortisol and ACTH levels. Furthermore, the temporal sequence between the two hormones suggests that the increase in plasma cortisol levels following brief high-intensity exercise is the result of ACTH-induced steroidogenesis in the adrenal cortex.