Bioengineering tools for probing intracellular events in T lymphocytes.
Bioengineering tools for probing intracellular events in T lymphocytes.
复制标题
DOI：
10.1002/wsbm.1510
复制
发表时间：
2021-07
影响因子：
3.1
通讯作者：
Shen K
中科院分区：
文献类型：
--
作者：
Zhang X;Mariano CF;Ando Y;Shen K
T lymphocytes are the central coordinator and executor of many immune functions. The activation and function of T lymphocytes are mediated through the engagement of cell surface receptors and regulated by a myriad of intracellular signaling network. Bioengineering tools, including imaging modalities and fluorescent probes, have been developed and employed to elucidate the cellular events throughout the functional lifespan of T cells. A better understanding of these events can broaden our knowledge in the immune systems biology, as well as accelerate the development of effective diagnostics and immunotherapies. Here we review the commonly used and recently developed techniques and probes for monitoring T lymphocyte intracellular events, following the order of intracellular events in T cells from activation, signaling, metabolism to apoptosis. The techniques introduced here can be broadly applied to other immune cells and cell systems.
登录
查看更多内容
影响因子：
56.9
作者：
Balint, S.;Muller, S.;Dustin, M. L.
通讯作者：
Dustin, M. L.
影响因子：
2.2
作者：
Banerjee, Pinaki P.;Orange, Jordan S.
通讯作者：
Orange, Jordan S.
DOI：
10.1016/j.bbrc.2015.02.117
发表时间：
2015-04-10
影响因子：
3.1
作者：
Cadra, Sophie;Gucciardi, Alexia;Lellouch, Annemarie C.
通讯作者：
Lellouch, Annemarie C.
影响因子：
38.3
作者：
Cai H;Muller J;Depoil D;Mayya V;Sheetz MP;Dustin ML;Wind SJ
通讯作者：
Wind SJ
影响因子：
9.8
作者：
Brown AC;Oddos S;Dobbie IM;Alakoskela JM;Parton RM;Eissmann P;Neil MA;Dunsby C;French PM;Davis I;Davis DM
通讯作者：
Davis DM