Efficacy of platelet rich plasma in third molar impaction surgery, PRP in third molar surgery
Efficacy of platelet rich plasma in third molar impaction surgery, PRP in third molar surgery
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富血小板血浆在第三磨牙阻生手术中的疗效、PRP 在第三磨牙手术中的疗效
DOI：
10.4103/2249-9725.127076
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
A. S. Arthur
中科院分区：
文献类型：
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作者：
J. Das;P. S. V. Parambath;A. S. Arthur
近年来，自体浓缩血小板主要是富含血小板的血浆在口腔颌面外科领域的应用具有重要意义。这些浓缩物具有促进硬组织和软组织愈合的能力。这种浓缩血小板的能力已经在下颌第三磨牙阻生手术后的愈合中进行了研究。不同的参数，如骨密度、软组织愈合、术后疼痛、肿胀和牙槽骨炎都被考虑在内。分别于术后第1、2、7天、1个月、2个月进行评估。找出每个参数的值，并将其制成表格。材料和方法：12例双侧下颌阻生第三磨牙患者，男7例，女5例。自体血小板浓缩。这是在其中一个插座上应用的，该插座被随机作为测试侧。另一个插口作为对照组。结果：疼痛和软组织愈合采用Mann-Whitney U检验进行统计学分析，试验侧疼痛差异有统计学意义，软组织愈合无统计学差异。骨密度和骨肿胀采用t检验。试验侧的骨密度值有统计学意义，而肿胀则没有太大的统计学意义。所有患者均未出现患侧牙槽骨炎。摘要与结论：富血小板血浆是一种可用于促进骨和软组织愈合的外科添加剂。它含有广泛的生长因子，这些生长因子对它们的治愈潜力负责。
The use of autologous platelet concentrates mainly platelet rich plasma has been of relevance recently in the field of Oral and Maxillofacial surgery. These concentrates had the ability to improve the hard and soft tissue healing. This ability of the platelet concentrates had been studied in the healing after mandibular third molar impaction surgery. The various parameters like bone density, soft tissue healing, postoperative pain, swelling, and alveolar osteitis were taken into account. The patients were evaluated on 1 st , 2 nd , 7 th day, 1 st month, and 2 nd month postoperatively. The values for each parameter were found out and tabulated. Materials and Methods: Twelve patients, seven males and five females with bilaterally impacted mandibular third molars were included in the study. Autologous platelets were concentrated. This was applied on one of the sockets, which was randomly taken as the test side. The other socket was treated as the control. Results: Statistical analysis was done using Mann-Whitney U test for pain and soft tissue healing, which revealed the values for pain being statistically significant for the test side and no statistical difference was noted for soft tissue healing. Bone density and swelling were analyzed with t-test. Bone density values were statistically significant for the test side, while swelling did not show much statistical significance. None of the patients presented with alveolar osteitis in any side. Summary and Conclusion: Platelet rich plasma is a surgical additive that can be used to improve bone and soft tissue healing. It contains a wide array of growth factors that are responsible for their healing potential.